Numerical study of the solidification process in biological tissue with blood flow and metabolism effects by the dual phase lag model

• Published in: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine Vol. 226; no. 5; p. 406
• Main Authors: Moradi, Amir, Ahmadikia, Hossein
• Format: Journal Article
• Language: English
• Published: England 01.05.2012
• Subjects: Algorithms; Blood Flow Velocity; Computer Simulation; Cryopreservation; Energy Transfer; Freezing; Humans; Models, Biological; Thermodynamics
• ISSN: 0954-4119
• DOI: 10.1177/0954411912441305

The bioheat transfer with phase change in biological tissues during the freezing process is simulated by the dual phase lag conduction heat transfer model. A numerical algorithm based on the enthalpy method is established to solve the solidification of biological tissues. The linearly temperature-dependent enthalpy (non-isothermal phase change) is considered here. The results of the parabolic heat conduction model for a slice of cucumber are compared with the experimental data. A comparison between dual phase lag and hyperbolic solutions with small values of relaxation times is applied in order to verify the corresponding parabolic solutions accuracy of the dual phase lag and hyperbolic solutions. The heating source effect owing to blood perfusion and metabolic heat on the heat transfer in a biological tissue subject to freezing process is studied. The relaxation time has an important influence on the transient temperature and temperature gradient. A major discrepancy among bioheat transfer models is found for zones closer to the cooling boundary. The heat source term, owing to blood flow and metabolism in a phase change problem in the biological tissue, has a significant influence on thermal effects of the subject tissue.