Jarisch‒Herxheimer reaction

Syphilis is caused by a spirochete, . Diagnosis of syphilis is made with a venereal disease research laboratory test. Treatment of choice is intramuscular injection benzathine Penicillin. The Jarisch‒Herxheimer reaction (JHR) is a transient immunological phenomenon that can occur in patients during...

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Bibliographic Details
Published inIndian Journal of Sexually Transmitted Diseases and AIDS Vol. 44; no. 1; pp. 79 - 81
Main Authors Gautam, Manjyot, Sethi, Sahil, Nadkarni, Nitin J
Format Journal Article
LanguageEnglish
Published India Medknow Publications & Media Pvt. Ltd 01.01.2023
Wolters Kluwer - Medknow
Subjects
Case Reports
Immune system
Penicillin
Side effects
Syphilis
Benzathine penicillin
immunological phenomenon
Jarisch‒Herxheimer
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Summary:Syphilis is caused by a spirochete, . Diagnosis of syphilis is made with a venereal disease research laboratory test. Treatment of choice is intramuscular injection benzathine Penicillin. The Jarisch‒Herxheimer reaction (JHR) is a transient immunological phenomenon that can occur in patients during treatment for syphilis with penicillin. It is a rare phenomenon but can be a potentially severe one. It manifests clinically with short-term constitutional symptoms such as fever, chills, headache, and myalgia, besides exacerbation of existing cutaneous lesions. We report the case of a 24-year-old man presenting with JHR posttreatment with benzathine penicillin.
ISSN:2589-0557
2589-0565
DOI:10.4103/ijstd.ijstd_107_22