Remifentanil and propofol total intravenous anaesthesia for thymectomy in myasthenia gravis

We report a case of trans-sternal thymectomy for myasthenia gravis using a non relaxant, total intravenous technique with propofol and remifentanil. This afforded excellent control of heart rate and pressor responses during surgery while allowing early return of spontaneous ventilation and extubatio...

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Published inAnaesthesia and intensive care Vol. 26; no. 2; pp. 210 - 212
Main Authors LORIMER, M, HALL, R
Format Journal Article
LanguageEnglish
Published Edgecliff Anaesthesia and Intensive Care 01.04.1998
Sage Publications Ltd
Subjects
Adolescent
Anesthetics, Combined - therapeutic use
Anesthetics, Intravenous - therapeutic use
Anesthetics. Neuromuscular blocking agents
Biological and medical sciences
Female
Humans
Medical sciences
Myasthenia Gravis - surgery
Neuropharmacology
Pharmacology. Drug treatments
Piperidines - therapeutic use
Propofol - therapeutic use
Remifentanil
Thymectomy - methods
Human
Neuromuscular diseases
Nervous system diseases
Agonist
Intravenous administration
μ Opioid receptor
General anesthesia
Narcotic analgesic
Remifentanil
Case study
Myasthenia gravis
Thymectomy
General anesthetic
Surgery
Propofol
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Summary:We report a case of trans-sternal thymectomy for myasthenia gravis using a non relaxant, total intravenous technique with propofol and remifentanil. This afforded excellent control of heart rate and pressor responses during surgery while allowing early return of spontaneous ventilation and extubation within nine minutes of termination of anaesthesia. Advantages and disadvantages of this approach versus relaxant and volatile techniques are discussed with particular reference to preservation of neuromuscular function.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:0310-057X
1448-0271
DOI:10.1177/0310057X9802600216