Early syphilis in a man with a negative Treponema pallidum enzyme immunoassay-IgM

Most serological tests for syphilis rely on an individual's ability to produce antibodies. A single screening test may be unreliable for screening in those with primary immunodeficiency. We present the first reported case of primary and secondary syphilis with negative Treponema pallidum enzyme...

Full description

Saved in:
Bibliographic Details
Published inInternational journal of STD & AIDS Vol. 22; no. 9; p. 529
Main Authors McCarty, E J, Keane, H, Quinn, K, Dinsmore, W W
Format Journal Article
LanguageEnglish
Published England 01.09.2011
Subjects
Adult
Antibodies, Bacterial - blood
Common Variable Immunodeficiency - complications
Humans
Immunoenzyme Techniques - methods
Immunoglobulin M - blood
Male
Syphilis - diagnosis
Syphilis - physiopathology
Syphilis Serodiagnosis
Treponema pallidum - immunology
Online AccessGet more information

Cover

More Information
Summary:Most serological tests for syphilis rely on an individual's ability to produce antibodies. A single screening test may be unreliable for screening in those with primary immunodeficiency. We present the first reported case of primary and secondary syphilis with negative Treponema pallidum enzyme immunoassay-IgM and Venereal Disease Research Laboratory tests in a man with common variable immunodeficiency.
ISSN:1758-1052
DOI:10.1258/ijsa.2009.009468