An introduction to causal mediation analysis

Causal mediation analysis has gained increasing attention in recent years. This article guides empirical researchers through the concepts and challenges of causal mediation analysis. I first clarify the difference between traditional and causal mediation analysis and highlight the importance of adju...

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Bibliographic Details
Published inAsia Pacific education review Vol. 25; no. 3; pp. 703 - 717
Main Author Qin, Xu
Format Journal Article
LanguageEnglish
Published Dordrecht Springer Netherlands 01.09.2024
Springer Nature B.V
교육연구소
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ISSN1598-1037
1876-407X
DOI10.1007/s12564-024-09962-5

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Summary:Causal mediation analysis has gained increasing attention in recent years. This article guides empirical researchers through the concepts and challenges of causal mediation analysis. I first clarify the difference between traditional and causal mediation analysis and highlight the importance of adjusting for the treatment-by-mediator interaction and confounders of the treatment–mediator, treatment–outcome, and mediator–outcome relationships. I then introduce the definition of causal mediation effects under the potential outcomes framework and different methods for the identification and estimation of the effects. After that, I highlight the importance of conducting a sensitivity analysis to assess the sensitivity of analysis results to potential unmeasured confounding. I also list various statistical software that can conduct causal mediation analysis and sensitivity analysis and provide suggestions for writing a causal mediation analysis paper. Finally, I briefly introduce some extensions that I made with my colleagues, including power analysis, multisite causal mediation analysis, causal moderated mediation analysis, and relaxing the assumption of no post-treatment confounding.
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ISSN:1598-1037
1876-407X
DOI:10.1007/s12564-024-09962-5