The role of total neoadjuvant therapy in locally advanced rectal cancer: a survey of specialists attending the All-Ireland Colorectal Cancer Conference 2022 including lead investigators of OPRA, PRODIGE-23 and RAPIDO

• Published in: Irish journal of medical science Vol. 193; no. 3; pp. 1183 - 1190
• Main Authors: O’Brien, Timothy, Hospers, Geke, Conroy, Thierry, Lenz, Heinz-Josef, Smith, Jesse Joshua, Andrews, Emmet, O’Neill, Brian, Leonard, Gregory
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.06.2024
• Subjects: Family Medicine; General Practice; Humans; Internal Medicine; Medical Oncology; Medicine; Medicine & Public Health; Neoadjuvant Therapy - methods; Neoadjuvant Therapy - statistics & numerical data; Original; Original Article; Rectal Neoplasms - pathology; Rectal Neoplasms - therapy; Surveys and Questionnaires; Rectal cancer; Total neoadjuvant therapy

Background The treatment of locally advanced rectal cancer (LARC) has evolved following recent landmark trials of total neoadjuvant therapy (TNT)—the delivery of preoperative chemotherapy sequenced with radiation. Aim To assess the preferences of colorectal surgery (CRS), radiation oncology (RO) and...