The Impact of Mushroom Polysaccharides on Gut Microbiota and Its Beneficial Effects to Host: A Review

• Published in: Carbohydrate polymers Vol. 250; p. 116942
• Main Authors: Yin, Chaomin, Noratto, Giuliana D., Fan, Xiuzhi, Chen, Zheya, Yao, Fen, Shi, Defang, Gao, Hong
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.12.2020
• Subjects: Agaricales - chemistry; beneficial effects; beneficial microorganisms; bioactive properties; culture media; dietary supplements; fruiting bodies; functional foods; Gastrointestinal Microbiome - drug effects; host health; Humans; intestinal microbiota; intestinal microorganisms; intestines; medicinal fungi; mushroom polysaccharides; mushrooms; mycelium; pathogens; polysaccharides; Polysaccharides - pharmacology; short chain fatty acids; beneficial effects; intestinal microbiota; mushroom polysaccharides; short chain fatty acids; host health
• ISSN: 0144-8617; 1879-1344; 1879-1344
• DOI: 10.1016/j.carbpol.2020.116942

•Isolation, purification and structural characterize methods of MP are summarized.•The main hydrolysis systems of gut microbiota to degrade MP are elaborated.•The impacts of MP on gut microbiota and bacteria metabolites are outlined.•The health beneficial effects of MP by targeting gut microbiota are discussed. Mushroom polysaccharides are a type of bioactive macromolecular which isolated from fruiting bodies, mycelia or fermentation broths of edible or medicinal fungus. Recently, mushroom polysaccharides have attracted a lot of attention for regulating gut microbiota via reducing the levels of pathogens and stimulating the growth of beneficial microorganisms, thus creating new possibilities for their use in nutraceutical and functional foods industries. The current review summarizes the isolation, purification and structural characterization methods of mushroom polysaccharides, the degradation of mushroom polysaccharides in intestine, the impacts of mushroom polysaccharides on gut microbiota community and short chain fatty acids (SCFAs) productivity, and the beneficial effects of mushroom polysaccharides to host by targeting gut microbiota. We hope this article can offer some theoretical bases and inspirations for the mechanism study of the bioactivity of mushroom polysaccharides.