Recent applications of bifunctional trityl groups

Triphenylmethyl derivatives represent an important class of dyestuffs as well as a useful family of protecting groups widely used in organic synthesis to transiently block various functional moieties. These applications are well documented and have been a subject of a number of reviews. Here we focu...

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Bibliographic Details
Published inChemical Society reviews Vol. 32; no. 3; pp. 170 - 180
Main Authors Shchepinov, M. S., Korshun, V. A.
Format Journal Article
LanguageEnglish
Published England 24.04.2003
Subjects
cations
chemical bonding
Combinatorial Chemistry Techniques - methods
crosslinking
fluorescence
Fluorescent Dyes - chemistry
mass spectrometry
Mass Spectrometry - methods
moieties
Oligonucleotides - chemical synthesis
Prodrugs - chemical synthesis
Triphenylmethyl Compounds - chemistry
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Summary:Triphenylmethyl derivatives represent an important class of dyestuffs as well as a useful family of protecting groups widely used in organic synthesis to transiently block various functional moieties. These applications are well documented and have been a subject of a number of reviews. Here we focus instead on some novel applications of a trityl which make good use of its ability to easily form a stabilised cation in combination with additional peripheral functionalities. Topics covered include applications in bioconjugation, cross-linking, mass-spectrometry, fluorescence and optics.
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ISSN:0306-0012
1460-4744
1460-4744
DOI:10.1039/b008900l