Clinicopathological and Prognostic Significance of Inhibitor of Apoptosis Protein (IAP) Family Members in Lung Cancer: A Meta-Analysis

• Published in: Cancers Vol. 13; no. 16; p. 4098
• Main Authors: Fung, Stephen, Knoefel, Wolfram Trudo, Krieg, Andreas
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 14.08.2021; MDPI
• Subjects: Apoptosis; Cancer therapies; Cell growth; Chemotherapy; Chromosomes; IAP protein; Kinases; Lung cancer; Lymph nodes; Lymphoma; Medical prognosis; Meta-analysis; Metastases; Metastasis; Mutation; Non-small cell lung carcinoma; Patients; Prognosis; Proteins; Survival analysis; Survivin; Systematic Review; Tumors; XIAP protein

Lung cancer is the most common cause of cancer-related death worldwide. Approximately 85% is non-small-cell and 15% is small-cell lung cancer. The inhibitor of apoptosis proteins (IAPs) represent a heterogeneous family of anti-apoptotic proteins, some members of which have been reported to correlate...