DRESS: a database of REfined solution NMR structures

• Published in: Proteins, structure, function, and bioinformatics Vol. 55; no. 3; pp. 483 - 486
• Main Authors: Nabuurs, Sander B., Nederveen, Aart J., Vranken, Wim, Doreleijers, Jurgen F., Bonvin, Alexandre M.J.J., Vuister, Geerten W., Vriend, Gert, Spronk, Christian A.E.M.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 15.05.2004
• Subjects: Databases, Protein; explicit solvent; Models, Molecular; molecular dynamics; nuclear magnetic resonance (NMR); Nuclear Magnetic Resonance, Biomolecular; protein structures; Proteins - chemistry; Solvents - chemistry; structure refinement; structure validation
• ISSN: 0887-3585; 1097-0134
• DOI: 10.1002/prot.20118

Several studies have shown that biomolecular NMR structures are often of lower quality when compared to crystal structures, and consequently they are often excluded from structural analyses. We present a publicly available database of re‐refined NMR structures, exhibiting significantly improved quality. This database (available at http://www.cmbi.kun.nl/dress/) presents a uniformly refined and validated set of structural models that improves the value of these NMR structures as input for experimental and theoretical studies in many fields of research. Proteins 2004. © 2004 Wiley‐Liss, Inc.