Remission of acquired pure red cell aplasia following plasma exchanges

A 22-year-old woman had an idiopathic pure red cell aplasia that failed to respond to high doses of corticosteroids. After a series of 10 plasma exchange procedures, bone marrow erythropoiesis and reticulocyte blood count returned to normal; the haematological remission has been now persistent for 1...

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Bibliographic Details
Published inScandinavian journal of haematology Vol. 34; no. 1; p. 13
Main Authors Khelif, A, Vu Van, H, Tremisi, J P, Alfonsi, F, Perrot, D, Motin, J, Viala, J J
Format Journal Article
LanguageEnglish
Published Denmark 01.01.1985
Subjects
Adult
Blood Transfusion
Erythrocyte Count
Erythrocyte Transfusion
Erythropoiesis
Female
Humans
Plasma Exchange
Prednisolone - therapeutic use
Red-Cell Aplasia, Pure - physiopathology
Red-Cell Aplasia, Pure - therapy
Reticulocytes
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Summary:A 22-year-old woman had an idiopathic pure red cell aplasia that failed to respond to high doses of corticosteroids. After a series of 10 plasma exchange procedures, bone marrow erythropoiesis and reticulocyte blood count returned to normal; the haematological remission has been now persistent for 12 months. The place of plasma exchange in the management of pure red cell aplasia and its mode of action will be discussed.
ISSN:0036-553X
DOI:10.1111/j.1600-0609.1985.tb00737.x