A double-blind controlled trial of a new alpha-1 blocking drug in the treatment of bladder outflow obstruction

Thirty-one patients with urodynamically proven bladder outflow obstruction were treated with Alfuzosin in a 3-month, double-blind, placebo-controlled study. The irritative symptoms of bladder outflow obstruction were improved significantly in the treatment group, according to both objective and subj...

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Bibliographic Details
Published inBritish journal of urology Vol. 57; no. 6; p. 657
Main Authors Ramsay, J W, Scott, G I, Whitfield, H N
Format Journal Article
LanguageEnglish
Published England 01.12.1985
Subjects
Adult
Blood Pressure - drug effects
Clinical Trials as Topic
Double-Blind Method
Humans
Male
Middle Aged
Prostatic Hyperplasia - complications
Quinazolines - adverse effects
Quinazolines - therapeutic use
Urinary Bladder Neck Obstruction - drug therapy
Urinary Bladder Neck Obstruction - etiology
Urodynamics - drug effects
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Summary:Thirty-one patients with urodynamically proven bladder outflow obstruction were treated with Alfuzosin in a 3-month, double-blind, placebo-controlled study. The irritative symptoms of bladder outflow obstruction were improved significantly in the treatment group, according to both objective and subjective evaluation. There was no objective evidence of a reduction in outflow resistance or obstruction in either group.
ISSN:0007-1331
DOI:10.1111/j.1464-410X.1985.tb07026.x