Hypothalamic/pituitary sarcoidosis

A patient is described with combined pulmonary and central nervous system sarcoidosis, including hypothalamic/pituitary involvement. Formal pituitary challenge testing was performed before steroid treatment and again eight months later. Diabetes insipidus, hyperprolactinemia, and anterior pituitary...

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Bibliographic Details
Published inAustralian and New Zealand journal of medicine Vol. 17; no. 2; p. 243
Main Authors Scott, I A, Stocks, A E, Saines, N
Format Journal Article
LanguageEnglish
Published Australia 01.04.1987
Subjects
Adult
Female
Humans
Hypothalamic Diseases - diagnosis
Hypothalamic Diseases - drug therapy
Pituitary Diseases - diagnosis
Pituitary Diseases - drug therapy
Pituitary Function Tests
Prednisone - therapeutic use
Sarcoidosis - diagnosis
Sarcoidosis - drug therapy
Tomography, X-Ray Computed
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Summary:A patient is described with combined pulmonary and central nervous system sarcoidosis, including hypothalamic/pituitary involvement. Formal pituitary challenge testing was performed before steroid treatment and again eight months later. Diabetes insipidus, hyperprolactinemia, and anterior pituitary hormone deficiencies were demonstrated and did not improve significantly in response to steroids. Hypothalamic/pituitary involvement is a rare complication of sarcoidosis, the incidence of which may be under-reported.
ISSN:0004-8291
DOI:10.1111/j.1445-5994.1987.tb00053.x