Trimethoprim associated fixed drug eruption

We report two cases of fixed drug eruption due to trimethoprim. Fixed drug eruption is a distinct entity characterized by the development of circular erythematous skin lesions which over a period of time become violaceous and leave an area of hyperpigmentation. Mucous membranes also may be affected....

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Bibliographic Details
Published inBritish journal of dermatology (1951) Vol. 116; no. 2; p. 241
Main Authors Hughes, B R, Holt, P J, Marks, R
Format Journal Article
LanguageEnglish
Published England 01.02.1987
Subjects
Adult
Drug Combinations - adverse effects
Drug Eruptions - etiology
Female
Humans
Sulfamethoxazole - adverse effects
Trimethoprim - adverse effects
Trimethoprim, Sulfamethoxazole Drug Combination
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Summary:We report two cases of fixed drug eruption due to trimethoprim. Fixed drug eruption is a distinct entity characterized by the development of circular erythematous skin lesions which over a period of time become violaceous and leave an area of hyperpigmentation. Mucous membranes also may be affected. With re-administration of the drug the lesions recur in the same area but may extend to further new areas with each challenge.
ISSN:0007-0963
DOI:10.1111/j.1365-2133.1987.tb05819.x