Contemporary variations of immune responsiveness during range expansion of two invasive rodents in Senegal

• Published in: Oikos Vol. 126; no. 3; pp. 435 - 446
• Main Authors: Diagne, Christophe, Gilot‐Fromont, Emmanuelle, Cornet, Stéphane, Husse, Laëtitia, Doucouré, Souleymane, Dalecky, Ambroise, Bâ, Khalilou, Kane, Mamadou, Niang, Youssoupha, Diallo, Mamoudou, Sow, Aliou, Fossati‐Gaschignard, Odile, Piry, Sylvain, Artige, Emmanuelle, Sembène, Mbacké, Brouat, Carine, Charbonnel, Nathalie
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.03.2017; Nordic Ecological Society
• Subjects: Animal biology; Biodiversity and Ecology; Environmental Sciences; Expansion; Global Changes; Hypotheses; Immunology; Life Sciences; Mastomys; Mastomys natalensis; Mus musculus domesticus; Nonnative species; Rattus rattus; Rodents; Vertebrate Zoology; ASE, Senegal
• ISSN: 0030-1299; 1600-0706
• DOI: 10.1111/oik.03470

Biological invasions provide unique opportunities for studying life history trait changes over contemporary time scales. As spatial spread may be related to changes in parasite communities, several hypotheses (such as the evolution of increased competitive ability (EICA) or EICA‐refined hypotheses) suggest immune changes in invasive species along invasion gradients. Although native hosts may be subject to similar changes in parasite selection pressures, their immune responses have been rarely investigated in invasion contexts. In this study, we evaluated immune variations for invasive house mice Mus musculus domesticus, invasive black rats Rattus rattus and native rodents Mastomys erythroleucus and Mastomys natalensis along well‐characterised invasion gradients in Senegal. We focused on antibody‐mediated (natural antibodies and complement) and inflammatory (haptoglobin) responses. One invasion route was considered for each invasive species, and environmental conditions were recorded. Natural‐antibody mediated responses increased between sites of long‐established invasion and recently invaded sites only in house mice. Both invasive species exhibited higher inflammatory responses at the invasion front than in sites of long‐established invasion. The immune responses of native species did not change with the presence of invasive species. These patterns of immune variations do not support the EICA and EICA refined hypotheses, and they rather suggest a higher risk of exposure to parasites on the invasion front. Altogether, these results provide a first basis to further assess the role of immune changes in invasion success.