Stimulation of interleukin 2 and interferon gamma production by leukotriene B4 in human lymphocyte cultures
Interleukin 2 (IL-2) and interferon-gamma (IFN) production by human lymphocytes was significantly enhanced in the presence of leukotriene B4 (LTB4) and indomethacin. Depletion of the T8+ suppressor cell subset of human T cells resulted in enhanced lymphokine production and further augmentation by LT...
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Published in | Prostaglandins leukotrienes and medicine Vol. 23; no. 2-3; pp. 207 - 210 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Edinburgh
Churchill Livingstone
01.08.1986
New York, NY |
Subjects | |
Online Access | Get full text |
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Summary: | Interleukin 2 (IL-2) and interferon-gamma (IFN) production by human lymphocytes was significantly enhanced in the presence of leukotriene B4 (LTB4) and indomethacin. Depletion of the T8+ suppressor cell subset of human T cells resulted in enhanced lymphokine production and further augmentation by LTB4. These findings suggest that LTB4 can regulate immune responses through its modulation of lymphokine production. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0262-1746 |
DOI: | 10.1016/0262-1746(86)90187-3 |