mRNA expression of novel CGRP1 receptors and their activity-modifying proteins in hypoxic rat lung

• Published in: American journal of physiology. Lung cellular and molecular physiology Vol. 280; no. 3; pp. 547 - L554
• Main Authors: Qing, Xin, Svaren, John, Keith, Ingegerd M
• Format: Journal Article
• Language: English
• Published: United States 01.03.2001
• Subjects: Animals; Base Sequence - genetics; Computer Systems; Hypoxia - metabolism; Intracellular Signaling Peptides and Proteins; Lung - metabolism; Male; Membrane Proteins - genetics; Molecular Sequence Data; Protein Isoforms - genetics; Rats; Rats, Sprague-Dawley; Receptor Activity-Modifying Protein 1; Receptor Activity-Modifying Protein 2; Receptor Activity-Modifying Protein 3; Receptor Activity-Modifying Proteins; Receptors, Adrenomedullin; Receptors, Calcitonin Gene-Related Peptide - genetics; Receptors, Cell Surface - genetics; Receptors, Chemokine; Receptors, CXCR; Receptors, G-Protein-Coupled; Receptors, Peptide - genetics; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - metabolism

Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin 53706 Calcitonin gene-related peptide (CGRP) is a potent vasodilator. Our group has reported that exogenous CGRP may prevent or reverse hypoxic pulmonary hypertension in rats. Th...