Erectile Dysfunction

Erectile dysfunction is defined as the inability to achieve and maintain an erection sufficient to permit satisfactory sexual intercourse. 1 It has been estimated to affect 20 million to 30 million men in the United States. 2 , 3 It may result from psychological, neurologic, hormonal, arterial, or c...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 342; no. 24; pp. 1802 - 1813
Main Author Lue, Tom F
Format Journal Article
LanguageEnglish
Published Boston, MA Massachusetts Medical Society 15.06.2000
Subjects
Adrenergic Antagonists - therapeutic use
Aging - physiology
Androgens - therapeutic use
Biological and medical sciences
Calcium
Drug Combinations
Erectile Dysfunction - drug therapy
Erectile Dysfunction - etiology
Erectile Dysfunction - physiopathology
Genital system. Reproduction
Gynecology. Andrology. Obstetrics
Humans
Kinases
Male
Male genital diseases
Medical sciences
Men
Muscular system
Non tumoral diseases
Penile Erection - physiology
Pharmacology. Drug treatments
Phosphodiesterase Inhibitors - therapeutic use
Piperazines - therapeutic use
Purines
Sexual disorders
Sildenafil Citrate
Sulfones
Human
Chemotherapy
Treatment
Androgen
Erection disorders
Pathogenesis
Enzyme inhibitor
Male
Physiology
Sildenafil
Male genital diseases
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Summary:Erectile dysfunction is defined as the inability to achieve and maintain an erection sufficient to permit satisfactory sexual intercourse. 1 It has been estimated to affect 20 million to 30 million men in the United States. 2 , 3 It may result from psychological, neurologic, hormonal, arterial, or cavernosal impairment or from a combination of these factors. In this article we provide a brief overview of the physiology of erection and the pathophysiology of erectile dysfunction, followed by a discussion of drug treatment for the disorder. Physiology of Penile Erection Penile erection is a neurovascular event modulated by psychological factors and hormonal status. . . .
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM200006153422407