Seizures after a Bier block with clonidine and lidocaine

A 47-yr-old man with history of complex regional pain syndrome type 1 underwent an IV Bier block with a mixture of lidocaine and clonidine. The tourniquet was deflated after 60 min, and approximately 10 min later he presented with complex partial seizures. The possible mechanisms for this are discus...

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Bibliographic Details
Published inAnesthesia and analgesia Vol. 99; no. 2; pp. 593 - 594
Main Authors AHMED, Shihab U, VALLEJO, Ricardo, HORD, E. Daniela
Format Journal Article
LanguageEnglish
Published Hagerstown, MD Lippincott 01.08.2004
Subjects
Adrenergic alpha-Agonists - adverse effects
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Anesthetics, Local - adverse effects
Biological and medical sciences
Clonidine - adverse effects
Epilepsy, Complex Partial - chemically induced
Humans
Lidocaine - adverse effects
Male
Medical sciences
Middle Aged
Nerve Block - adverse effects
Reflex Sympathetic Dystrophy - complications
Nervous system diseases
Epilepsy
Central nervous system disease
Anesthesia
Clonidine
Lidocaine
Cerebral disorder
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Summary:A 47-yr-old man with history of complex regional pain syndrome type 1 underwent an IV Bier block with a mixture of lidocaine and clonidine. The tourniquet was deflated after 60 min, and approximately 10 min later he presented with complex partial seizures. The possible mechanisms for this are discussed, and the effects of clonidine, lidocaine, and the mixture of both are reviewed, as are four additional published cases reporting seizures after the administration of clonidine.
ISSN:0003-2999
1526-7598
DOI:10.1213/01.ANE.0000123011.00161.C9