Frailty in cerebellar ischemic stroke—The significance of temporal muscle thickness

• Published in: Frontiers in neurology Vol. 14; p. 1193685
• Main Authors: Dubinski, Daniel, Won, Sae-Yeon, Mattes, Isabell, Trnovec, Svorad, Behmanesh, Bedjan, Cantré, Daniel, Baumgarten, Peter, Dinc, Nazife, Konczalla, Juergen, Wittstock, Matthias, Freiman, Thomas M., Gessler, Florian
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 26.09.2023
• Subjects: cerebellar stroke; ischemic stroke; Neurology; out-come; posterior fossa; sarcopenia; temporal muscle thickness
• ISSN: 1664-2295; 1664-2295
• DOI: 10.3389/fneur.2023.1193685

While comprising only 2% of all ischemic strokes, cerebellar strokes are responsible for substantial morbidity and mortality due to their subtle initial presentation and the morbidity of posterior fossa swelling. Furthermore, low temporal muscle thickness (TMT) has recently been identified as a prognostic imaging parameter to assess patient frailty and outcome. We analyzed radiological and clinical data sets of 282 patients with cerebellar ischemic stroke. Our analysis showed a significant association between low TMT, reduced NIHSS and mRS at discharge ( p = 0.035, p = 0.004), and reduced mRS at 12 months ( p = 0.001). TMT may be used as a prognostic imaging marker and objective tool to assess outcomes in patients with cerebellar ischemic stroke.