Toxic, but beneficial compounds from endophytic fungi of Carica papaya

Fungi remain a promising source of novel biologically active compounds with potentials in drug discovery and development. This study was aimed at investigating the secondary metabolites from endophytic and associated with leaves of collected from Agulu, Anambra State, Nigeria. Isolation of the endop...

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Published inThe eurobiotech journal Vol. 3; no. 2; pp. 105 - 111
Main Authors Eze, Peter M., Abonyi, Dominic O., Abba, Chika C., Proksch, Peter, Okoye, Festus B. C., Esimone, Charles O.
Format Journal Article
LanguageEnglish
Published Sciendo 01.04.2019
Subjects
carica papaya
Endophytic fungi
epicoccum sorghinum
fusarium equiseti
secondary metabolites
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Summary:Fungi remain a promising source of novel biologically active compounds with potentials in drug discovery and development. This study was aimed at investigating the secondary metabolites from endophytic and associated with leaves of collected from Agulu, Anambra State, Nigeria. Isolation of the endophytic fungi, taxonomic identification, fermentation, extraction and isolation of fungal secondary metabolites were carried out using standard procedures. Chromatographic separation and spectroscopic analyses of the fungal secondary metabolites yielded three toxigenic compounds - equisetin and its epimer 5’- epiequisetin from and tenuazonic acid from These compounds are known to possess several beneficial biological properties that can be explored for pharmaceutical, agricultural or industrial purposes.
ISSN:2564-615X
2564-615X
DOI:10.2478/ebtj-2019-0012