Development and Validation of a Liquid Chromatographic Method for Monitoring of Process-Related Synthetic Organic Impurities of Profenofos in Technical Products

• Published in: Journal of chromatographic science Vol. 41; no. 8; pp. 418 - 421
• Main Authors: Rao, R. Nageswara, Raju, D. Naga, Venkateswarlu, N., Rao, B. Vittal, Parvathi, N., Manjula, A., Reddy, G.N., Gawali, P.B., Sreekanth, M., Rao, P. Nageswara
• Format: Journal Article
• Language: English
• Published: Niles, IL Oxford University Press 01.09.2003; Preston Publications
• Subjects: Biological and medical sciences; Chemical control; Chromatography, High Pressure Liquid - methods; Control; Fundamental and applied biological sciences. Psychology; Insecticides - chemistry; Organic Chemicals - analysis; Organothiophosphates - chemistry; Phytopathology. Animal pests. Plant and forest protection; Protozoa. Invertebrates; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Trace analysis; Validation; Elution; Gradient; Chemical analysis; Insecticide; Impurity; Pesticides; HPLC chromatography; Purity control; Reversed phase chromatography; Ultraviolet detector; Quality control; Organophosphorus compounds; Quantitative analysis

A simple and rapid reversed-phase high-performance liquid chromatographic method for the monitoring of process-related synthetic organic impurities of profenofos (PFS) is developed. Impurities are separated and determined on a reversed-phase Hypersil C18 column using gradient elution of 50mM ammoniu...