Transmission dynamics of cholera: Mathematical modeling and control strategies

•We propose a model to describe the transmission of Cholera.•Basic reproduction number of Cholera transmission model are obtained.•Global dynamics are presented.•Vaccination is more effective than disinfection in eradicating Cholera. Cholera, as an endemic disease around the world, has generated gre...

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Published inCommunications in nonlinear science & numerical simulation Vol. 45; pp. 235 - 244
Main Authors Sun, Gui-Quan, Xie, Jun-Hui, Huang, Sheng-He, Jin, Zhen, Li, Ming-Tao, Liu, Liqun
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier B.V 01.04.2017
Elsevier Science Ltd
Subjects
Cholera
Disease control
Disease transmission
Disinfection
Drinking water
Dynamical model
Environmental management
Immunization
Mathematical analysis
Mathematical models
Vaccination
China
Disinfection
Dynamical model
Cholera
Vaccination
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ISSN1007-5704
1878-7274
DOI10.1016/j.cnsns.2016.10.007

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Summary:•We propose a model to describe the transmission of Cholera.•Basic reproduction number of Cholera transmission model are obtained.•Global dynamics are presented.•Vaccination is more effective than disinfection in eradicating Cholera. Cholera, as an endemic disease around the world, has generated great threat to human society and caused enormous morbidity and mortality with weak surveillance system. In this paper, we propose a mathematical model to describe the transmission of Cholera. Moreover, basic reproduction number and the global dynamics of the dynamical model are obtained. Then we apply our model to characterize the transmission process of Cholera in China. It was found that, in order to avoid its outbreak in China, it may be better to increase immunization coverage rate and make effort to improve environmental management especially for drinking water. Our results may provide some new insights for elimination of Cholera.
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ISSN:1007-5704
1878-7274
DOI:10.1016/j.cnsns.2016.10.007