Automatic detection of epileptic seizures in EEG using discrete wavelet transform and approximate entropy

• Published in: Expert systems with applications Vol. 36; no. 2; pp. 2027 - 2036
• Main Author: Ocak, Hasan
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.03.2009
• Subjects: Approximate entropy; Discrete wavelet transform; Seizure detection; Surrogate data analysis; Approximate entropy; Discrete wavelet transform; Seizure detection; Surrogate data analysis
• ISSN: 0957-4174; 1873-6793
• DOI: 10.1016/j.eswa.2007.12.065

In this study, a new scheme was presented for detecting epileptic seizures from electro-encephalo-gram (EEG) data recorded from normal subjects and epileptic patients. The new scheme was based on approximate entropy (ApEn) and discrete wavelet transform (DWT) analysis of EEG signals. Seizure detection was accomplished in two stages. In the first stage, EEG signals were decomposed into approximation and detail coefficients using DWT. In the second stage, ApEn values of the approximation and detail coefficients were computed. Significant differences were found between the ApEn values of the epileptic and the normal EEG allowing us to detect seizures with over 96% accuracy. Without DWT as preprocessing step, it was shown that the detection rate was reduced to 73%. The analysis results depicted that during seizure activity EEG had lower ApEn values compared to normal EEG. This suggested that epileptic EEG was more predictable or less complex than the normal EEG. The data was further analyzed with surrogate data analysis methods to test for evidence of nonlinearities. It was shown that epileptic EEG had significant nonlinearity whereas normal EEG behaved similar to Gaussian linear stochastic process.