Successful conservative treatment of endocervical adenocarcinoma stage Ib1 diagnosed early in pregnancy

• Published in: Acta obstetricia et gynecologica Scandinavica Vol. 87; no. 2; pp. 250 - 253
• Main Authors: Van Calsteren, Kristel, Hanssens, Myriam, Moerman, Philippe, Orye, Guy, Bielen, Didier, Vergote, Ignace, Amant, Frederic
• Format: Journal Article
• Language: English
• Published: Oxford, UK Informa UK Ltd 01.01.2008; Blackwell Publishing Ltd
• Subjects: Adenocarcinoma - diagnosis; Adenocarcinoma - surgery; Adult; Cervix Uteri - surgery; conservative management; Early Diagnosis; early pregnancy; Endocervical adenocarcinoma; Female; Humans; Lymph Node Excision; Pregnancy; Pregnancy Complications, Neoplastic - diagnosis; Pregnancy Complications, Neoplastic - surgery; Pregnancy Trimester, First; Uterine Cervical Neoplasms - diagnosis; Uterine Cervical Neoplasms - surgery
• ISSN: 0001-6349; 1600-0412
• DOI: 10.1080/00016340701870794

Traditionally when cervical cancer is diagnosed during the first trimester of pregnancy, oncological treatment is given priority despite the pregnant state. A 32-year-old primigravida was diagnosed with invasive endocervical adenocarcinoma stage Ib1 at 8 weeks' gestation. As the patient wanted to preserve the pregnancy, an amputation of the anterior cervix and retroperitoneal pelvic lymphadenectomy were performed. Based on favourable prognostic markers, we decided to maintain the pregnancy with careful cytological and histological follow-up. The patient gave birth at term to a healthy boy, and 18 months after the delivery there is no evidence of recurrent disease. In the absence of poor prognostic markers, we decided to adopt a conservative approach for cervical adenocarcinoma in a pregnant patient at 8 weeks' gestation.