Potential and Therapeutic Roles of Diosmin in Human Diseases

• Published in: Biomedicines Vol. 10; no. 5; p. 1076
• Main Authors: Huwait, Etimad, Mobashir, Mohammad
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 06.05.2022; MDPI
• Subjects: anti-cardiovascular; anti-diabetic; anti-inflammatory; anti-oxidant; Apoptosis; Binding sites; Biomarkers; Bladder; Breast cancer; Cell cycle; Chronic illnesses; Colon; Diabetes; Diabetes mellitus; Diosmin; Disease; Enzymes; Esophagus; Flavonoids; Free radicals; Hemorrhoids; Hypoxia; Inflammation; Investigations; Ischemia; Liver cancer; Medicin och hälsovetenskap; Medicinal plants; Metabolism; Neuroprotection; Neutrophils; Oxidative stress; Phytochemicals; Plants; Prostate; Proteins; Review; target pathways; target pathways; anti-cardiovascular; anti-inflammatory; anti-oxidant; anti-diabetic; anti-cancer; Diosmin
• ISSN: 2227-9059; 2227-9059
• DOI: 10.3390/biomedicines10051076

Because of their medicinal characteristics, effectiveness, and importance, plant-derived flavonoids have been a possible subject of research for many years, particularly in the last decade. Plants contain a huge number of flavonoids, and Diosmin, a flavone glycoside, is one of them. Numerous and studies have validated Diosmin's extensive range of biological capabilities which present antioxidative, antihyperglycemic, anti-inflammatory, antimutagenic, and antiulcer properties. We have presented this review work because of the greater biological properties and influences of Diosmin. We have provided a brief overview of Diosmin, its pharmacology, major biological properties, such as anti-cancer, anti-diabetic, antibacterial, anticardiovascular, liver protection, and neuroprotection, therapeutic approach, potential Diosmin targets, and pathways that are known to be associated with it.