An update on the use of ophthalmic ketorolac tromethamine 0.4

Ketorolac tromethamine 0.4% ophthalmic solution, a recent reformulation of the original ketorolac tromethamine 0.5% solution, is indicated for the reduction of ocular pain and burning/stinging following cataract and refractive surgery. Studies have demonstrated that ketorolac tromethamine 0.4% has e...

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Bibliographic Details
Published inExpert opinion on pharmacotherapy Vol. 7; no. 1; p. 99
Main Authors Perry, Henry D, Donnenfeld, Eric D
Format Journal Article
LanguageEnglish
Published England 01.01.2006
Subjects
Administration, Topical
Animals
Anti-Inflammatory Agents, Non-Steroidal - administration & dosage
Eye Diseases - drug therapy
Eye Diseases - metabolism
Humans
Ketorolac Tromethamine - administration & dosage
Prostaglandins - biosynthesis
Uveitis, Anterior - drug therapy
Uveitis, Anterior - metabolism
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Summary:Ketorolac tromethamine 0.4% ophthalmic solution, a recent reformulation of the original ketorolac tromethamine 0.5% solution, is indicated for the reduction of ocular pain and burning/stinging following cataract and refractive surgery. Studies have demonstrated that ketorolac tromethamine 0.4% has equivalent efficacy to ketorolac tromethamine 0.5% in reducing postsurgical inflammation and controlling pain. Several studies have demonstrated that, as well as reducing pain and ocular inflammation, ketorolac tromethamine 0.4% effectively treats cystoid macular oedema, inhibits miosis and may prevent cystoid macular oedema when used both pre- and postoperatively. Ketorolac tromethamine 0.4% is a versatile agent and is effective when used as either monotherapy or as an adjunct therapy to steroids.
ISSN:1744-7666
DOI:10.1517/14656566.7.1.99