Comparison between rocuronium and succinylcholine for rapid sequence induction: A systematic review and network meta-analysis of randomized clinical trials

• Published in: Journal of clinical anesthesia Vol. 72; p. 110265
• Main Authors: de Carvalho, Clístenes Crístian, da Silva, Danielle Melo, de Athayde Regueira, Stéphanie Leite Pessoa, de Souza, Ana Beatriz Sá, Rego, Caroline Oliveira, Ramos, Isabella Beserra, dos Santos Neto, Jayme Marques
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2021; Elsevier Limited
• Subjects: Androstanols - adverse effects; Bias; Clinical trials; Data collection; Humans; Intubation; Intubation, Intratracheal - adverse effects; Meta-analysis; Network Meta-Analysis; Neuromuscular agents; Neuromuscular blockade; Neuromuscular Depolarizing Agents - adverse effects; Personal relationships; Randomized Controlled Trials as Topic; Rapid sequence induction; Rapid Sequence Induction and Intubation; Regression analysis; Rocuronium; Succinylcholine; Succinylcholine - adverse effects; Systematic review; Ventilation; Neuromuscular blockade; Neuromuscular agents; Rapid sequence induction; Succinylcholine; Rocuronium
• ISSN: 0952-8180; 1873-4529
• DOI: 10.1016/j.jclinane.2021.110265

Rocuronium has yet an available swift reversal agent: sugammadex [5,6]. [...]succinylcholine may abridge time for oxygen desaturation due to its related muscular fasciculations [7]. [...]apart from contraindications, currently available evidence is not enough to favor either rocuronium or succinylcholine for RSI. Study design, screening, data collection, article review.Financial disclosures None.Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.