Confabulations in episodic memory are associated with delusions in Alzheimer's disease

Although confabulations and delusions are observed in Alzheimer's disease, the relationship between the 2 has not been fully investigated. This study involved 50 patients with Alzheimer's disease and 10 healthy participants. After the patients were divided into delusional and nondelusional...

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Published inJournal of geriatric psychiatry and neurology Vol. 20; no. 1; p. 34
Main Authors Lee, Eunjoo, Meguro, Kenichi, Hashimoto, Ryusaku, Meguro, Mitsue, Ishii, Hiroshi, Yamaguchi, Satoshi, Mori, Etsuro
Format Journal Article
LanguageEnglish
Published United States 01.03.2007
Subjects
Aged
Aged, 80 and over
Alzheimer Disease - diagnosis
Alzheimer Disease - psychology
Amnesia - diagnosis
Amnesia - psychology
Delusions - diagnosis
Delusions - psychology
Female
Humans
Male
Mental Disorders - diagnosis
Mental Disorders - psychology
Mental Recall
Neuropsychological Tests
Reference Values
Repression, Psychology
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Summary:Although confabulations and delusions are observed in Alzheimer's disease, the relationship between the 2 has not been fully investigated. This study involved 50 patients with Alzheimer's disease and 10 healthy participants. After the patients were divided into delusional and nondelusional groups, confabulations and cognitive function were assessed. No confabulations appeared in the healthy participants, and only patients with Alzheimer's disease showed confabulations. The delusional group produced more confabulations on episodic subjects than on semantic subjects. There was a correlation between cognitive impairment and confabulations in semantic memory. These findings suggest that different mechanisms are involved in confabulations between semantic and episodic memories.
ISSN:0891-9887
DOI:10.1177/0891988706292760