Preparation and properties of chitosan derivative/poly(vinyl alcohol) blend film crosslinked with glutaraldehyde

• Published in: Carbohydrate polymers Vol. 84; no. 1; pp. 465 - 470
• Main Authors: Yu, Qian, Song, Yanan, Shi, Xiaomei, Xu, Chunye, Bin, Yuezhen
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 11.02.2011; Elsevier
• Subjects: alcohols; Antibacterial; antibacterial properties; Applied sciences; aqueous solutions; chitosan; Chitosan derivative; Crosslinking; Escherichia coli; Exact sciences and technology; gels; glutaraldehyde; mixing; Natural polymers; Physicochemistry of polymers; Poly(vinyl alcohol); polyvinyl alcohol; Staphylococcus aureus; Starch and polysaccharides; Swelling; Crosslinking; Poly(vinyl alcohol); Antibacterial; Chitosan derivative; Swelling; Biological properties; Polymer blends; Property composition relationship; Glutaral; Experimental study; Bactericidal effect; Colloidal gel; Polyelectrolyte; Polyvinylalcohol; Chitosan derivatives; Preparation; Reaction mechanism; Oside polymer; Kinetics; Quaternary ammonium polymer
• ISSN: 0144-8617; 1879-1344
• DOI: 10.1016/j.carbpol.2010.12.006

Novel crosslinked blend films of N-(2-hydroxy)propyl-3-trimethylammonium chitosan chloride (HTCC) and poly(vinyl alcohol) (PVA) were prepared by mixing their aqueous solutions followed by crosslinking with glutaraldehyde (GA). The effects of the GA content and ratio of HTCC to PVA on the appearance, swelling, gel content, morphology and antibacterial activities of blend films were studied and a possible mechanism of crosslinking was proposed based on the results. It was found that the equilibrium degree of swelling (ESD) increased with the increasing content of HTCC, but decreased with the content of GA. The ESD was a maximum (212%) when the ratio of HTCC/PVA/GA was 60/40/2 (wt). Antibacterial activities against Staphylococcus aureus and Escherichia coli of the blend films were weakened slightly by crosslinking, but still showed substantial antibacterial activity. These results demonstrate that, not only the PVA, but also the HTCC reacted with GA. It was the amino groups on HTCC that was un-substituted by quaternary ammonium salt, which reacted with the aldehyde groups on GA.