Relative value of three whole-body MR approaches for PET-MR, including gadofosveset-enhanced MR, in comparison to PET-CT
Evaluate MR protocol for PET-MR including coronal DWI (cDWI), fat-suppressed T2 (T2w), and gadofosveset-enhanced T1 (CE). 18 patients underwent same-day PET-CT and PET-MR. Image quality and performance of each sequence, and combination of all three sequences, was evaluated with respect to PET-CT. Le...
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Published in | Clinical imaging Vol. 48; pp. 62 - 68 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
01.03.2018
Elsevier Limited |
Subjects | |
Online Access | Get full text |
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Summary: | Evaluate MR protocol for PET-MR including coronal DWI (cDWI), fat-suppressed T2 (T2w), and gadofosveset-enhanced T1 (CE).
18 patients underwent same-day PET-CT and PET-MR. Image quality and performance of each sequence, and combination of all three sequences, was evaluated with respect to PET-CT.
Lesion conspicuity was best on cDWI, while delineation was best on CE. Considering all three sequences combined, both readers showed good sensitivity and specificity (>80%). Relative sensitivity was highest on CE and lowest on T2w.
Whole-body MR performed well in detecting malignant lesions compared to PET-CT. CE showed overall highest performance.
•MRI protocol proposed for whole-body PET-MRI, including coronal DWI, fat-suppressed T2, and gadofosveset-enhanced T1•MR sequences evaluated for image quality and performance compared to PET-CT•Whole-body MR performed well in detecting malignant lesion•Highest relative sensitivity was achieved with gadofosveset-enhanced T1 sequence |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0899-7071 1873-4499 |
DOI: | 10.1016/j.clinimag.2017.09.016 |