An ultra-low cost NMR device with arbitrary pulse programming

• Published in: Journal of magnetic resonance (1997) Vol. 255; pp. 100 - 105
• Main Authors: Chen, Hsueh-Ying, Kim, Yaewon, Nath, Pulak, Hilty, Christian
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2015
• Subjects: NMR hardware; Portable NMR; Relaxometry; Portable NMR; Relaxometry; NMR hardware
• ISSN: 1090-7807; 1096-0856
• DOI: 10.1016/j.jmr.2015.02.011

[Display omitted] •An NMR spectrometer is based on an ultra-low cost electronics board with FPGA.•Few auxiliary components are needed and can be assembled in a typical NMR lab.•Arbitrary pulse sequences with accurate timing are generated in the MHz range. Ultra-low cost, general purpose electronics boards featuring microprocessors or field programmable gate arrays (FPGA) are reaching capabilities sufficient for direct implementation of NMR spectrometers. We demonstrate a spectrometer based on such a board, implemented with a minimal need for the addition of custom electronics and external components. This feature allows such a spectrometer to be readily implemented using typical knowledge present in an NMR laboratory. With FPGA technology, digital tasks are performed with precise timing, without the limitation of predetermined hardware function. In this case, the FPGA is used for programming of arbitrarily timed pulse sequence events, and to digitally generate required frequencies. Data acquired from a 0.53T permanent magnet serves as a demonstration of the flexibility of pulse programming for diverse experiments. Pulse sequences applied include a spin–lattice relaxation measurement using a pulse train with small-flip angle pulses, and a Carr–Purcell–Meiboom–Gill experiment with phase cycle. Mixing of NMR signals with a digitally generated, 4-step phase-cycled reference frequency is further implemented to achieve sequential quadrature detection. The flexibility in hardware implementation permits tailoring this type of spectrometer for applications such as relaxometry, polarimetry, diffusometry or NMR based magnetometry.