Eosinophilia

A marked accumulation of eosinophils occurs in several important disorders, such as allergic diseases, parasitic infections, and cancer. 1 The level of eosinophils in the body is normally tightly regulated. In normal subjects, eosinophils account for only a small minority of peripheral-blood leukocy...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 338; no. 22; pp. 1592 - 1600
Main Author Rothenberg, Marc E
Format Journal Article
LanguageEnglish
Published Boston, MA Massachusetts Medical Society 28.05.1998
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Summary:A marked accumulation of eosinophils occurs in several important disorders, such as allergic diseases, parasitic infections, and cancer. 1 The level of eosinophils in the body is normally tightly regulated. In normal subjects, eosinophils account for only a small minority of peripheral-blood leukocytes, and their presence in tissues is primarily limited to the gastrointestinal mucosa. 2 In certain disease states, however, eosinophils can selectively accumulate in the peripheral blood or any tissue in the body. Any perturbation that results in eosinophilia, defined here as an abnormal accumulation of eosinophils in blood or tissue, can have profound clinical effects. Eosinophilia may be harmful, . . .
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ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM199805283382206