Hemoperitoneum from Spontaneous Rupture of a Liver Cell Adenoma in a Male with Hyperthyroidism

• Published in: The American surgeon Vol. 68; no. 7; pp. 582 - 583
• Main Authors: Adusumilli, Prasad S., Lee, Byrne, Parekh, Kalpaj, Dolgopolov, Sergei
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.07.2002; Southeastern Surgical Congress; SAGE PUBLICATIONS, INC
• Subjects: Abdomen; Adenoma, Liver Cell - complications; Adenoma, Liver Cell - surgery; Adult; Biological and medical sciences; Gastroenterology. Liver. Pancreas. Abdomen; Hemoperitoneum - etiology; Hepatectomy; Humans; Hyperthyroidism - complications; Liver; Liver Neoplasms - complications; Liver Neoplasms - surgery; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Male; Males; Medical disorders; Medical sciences; Other diseases. Semiology; Rupture, Spontaneous; Thyroid gland; Tumors; Endocrinopathy; Human; Hemoperitoneum; Effusion; Radiodiagnosis; Liver; Hyperthyroidism; Spontaneous; Thyroid diseases; Rupture; Hepatic disease; Male; Adenoma; Case study; Abdominal disease; Young adult; Digestive diseases; Medical imagery; Complication; Computerized axial tomography; Benign neoplasm; Peritoneum
• ISSN: 0003-1348; 1555-9823
• DOI: 10.1177/000313480206800704

Spontaneous liver rupture is uncommon, is difficult to diagnose, and carries a high mortality. Liver cell adenoma is a rare benign liver tumor with increasing incidence in women on oral contraceptive pills, and they have been reported to rupture spontaneously. In men such a phenomenon is an extreme rarity. In animal experiments thyroid hormone is proven to play a role in the growth of liver cell-derived neoplasms as they do in normal hepatocyte proliferation. An association of liver cell adenoma and hyperthyroidism in humans has not been previously reported. We present the successful management of an unusual case of spontaneous hemoperitoneum from rupture of a liver cell adenoma in a young man with hyperthyroidism.