New ellagitannins from Tiencha and their inhibitory activity against dental plaque

Four new galloyl-oxygen-diphenyl (GOD)-type ellagitannins, brambliins A–D ( 1 – 4 ), were isolated from the leaves of Rubus suavissimus . Their structures were elucidated by extensive spectroscopic analyses and the absolute configurations of 1 – 4 were determined by chemical and phytochemical eviden...

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Bibliographic Details
Published inJournal of natural medicines Vol. 71; no. 3; pp. 545 - 552
Main Authors Nakano, Fusako, Miyoshi, Shozo, Murakami, Toshiyuki
Format Journal Article
LanguageEnglish
Published Tokyo Springer Japan 01.07.2017
Springer Nature B.V
Subjects
Biomedical and Life Sciences
Biomedicine
Complementary & Alternative Medicine
Dental Plaque
Herbal medicine
Hydrolyzable Tannins - chemistry
Hydrolyzable Tannins - isolation & purification
Hydrolyzable Tannins - pharmacology
Medicinal Chemistry
Molecular Structure
Oral diseases
Oral hygiene
Original Paper
Pharmacology/Toxicology
Pharmacy
Phytochemicals
Plant Extracts - chemistry
Plant Extracts - pharmacology
Plant Leaves - chemistry
Plant Sciences
Rubus - chemistry
Anti-dental plaque
GOD-type ellagitannin
Tiencha
Brambliin
Rubus suavissimus
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Summary:Four new galloyl-oxygen-diphenyl (GOD)-type ellagitannins, brambliins A–D ( 1 – 4 ), were isolated from the leaves of Rubus suavissimus . Their structures were elucidated by extensive spectroscopic analyses and the absolute configurations of 1 – 4 were determined by chemical and phytochemical evidence. These GOD-type ellagitannins inhibited the formation of dental plaque, which is beneficial for oral hygiene.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1340-3443
1861-0293
DOI:10.1007/s11418-017-1090-9