Synthesis of Highly Fluorinated Chloroformates and Their Use as Derivatizing Agents for Hydrophilic Compounds and Drinking-Water-Disinfection By-Products

A rapid, safe, and efficient procedure was developed to synthesize, on a small scale, fluorinated chloroformates often required to perform analytical derivatizations. This new family of agents allows straightforward derivatization of highly polar compounds (with multiple hydroxy, carboxy, and amino...

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Bibliographic Details
Published inHelvetica chimica acta Vol. 87; no. 2; pp. 370 - 375
Main Authors Vincenti, Marco, Ghiglione, Nicoletta, Valsania, Maria Carmen, Davit, Patrizia, Richardson, Susan D.
Format Journal Article
LanguageEnglish
Published Zürich WILEY-VCH Verlag 01.02.2004
WILEY‐VCH Verlag
Wiley
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
GAS-CHROMATOGRAPHY
MEDIATED DERIVATIZATION
AMINO-ACIDS
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Summary:A rapid, safe, and efficient procedure was developed to synthesize, on a small scale, fluorinated chloroformates often required to perform analytical derivatizations. This new family of agents allows straightforward derivatization of highly polar compounds (with multiple hydroxy, carboxy, and amino substituents) in the aqueous phase, compatible with GC and GC/MS analysis. A goal of this work was to develop a derivatization procedure that would enable the detection and identification of highly polar disinfection by‐products in drinking water.
Bibliography:ark:/67375/WNG-ZVRSRC5W-X
istex:54A98BFFE4744F374C34F423A3E1E8F9F7CE01C4
ArticleID:HLCA200490034
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0018-019X
1522-2675
DOI:10.1002/hlca.200490034