Extended Survival by Urgent Liver Retransplantation after Using a First Graft with Metastasis from Initially Unrecognized Donor Sarcoma

• Published in: American journal of transplantation Vol. 5; no. 6; pp. 1559 - 1561
• Main Authors: Ortiz, Jorge A., Manzarbeitia, Cosme, Noto, Khristian A., Rothstein, Kenneth D., Araya, Victor A., Munoz, Santiago J., Reich, David J.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Munksgaard International Publishers 01.06.2005; Blackwell
• Subjects: Aortic Diseases - pathology; Biological and medical sciences; Carcinoma, Renal Cell - pathology; Disease-Free Survival; Donor malignancy; Emergency Medical Services; Graft Survival; Humans; Kidney Neoplasms - pathology; Liver Transplantation; Male; Medical sciences; Middle Aged; Neoplasms, Multiple Primary - pathology; Reoperation; sarcoma; Sarcoma - pathology; Sarcoma - secondary; Splenic Neoplasms - pathology; Splenic Neoplasms - secondary; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tissue Donors; Human; Reoperation; Prognosis; Sarcoma; Digestive system; Liver; Transplantation; Malignancy; Metastasis; Malignant tumor; Homotransplantation; Survival; Treatment; Donor; Surgery; Tumor progression; Graft; Donor malignancy; liver transplantation
• ISSN: 1600-6135; 1600-6143
• DOI: 10.1111/j.1600-6143.2005.00824.x

A 58‐year‐old man underwent orthotopic liver transplantation for polycystic liver disease. Shortly after the procedure, it was discovered that the donor harbored a sarcoma of the aortic arch that had metastasized to the spleen, and bilateral renal cell carcinomas. The two sole organ recipients, our liver recipient and a lung recipient at another institution, were both listed for urgent retransplantation, which they received from the same second donor. The liver explant contained metastatic sarcoma. Twenty‐four months survival following lung retransplantation has been previously reported. We report the 76‐month disease‐free survival in the liver recipient.