Survey of diurnal weight gain and urine volume in chronic schizophrenia

We found diurnal weight gain to be abnormal among 39 chronic schizophrenic patients. The patients were weighed and urine samples obtained weekly for three weeks at 7 a.m. and 4 p.m. We normalized the dirunal weight gain (NDWG) as a percentage by subtracting the 7 a.m. weight from the 4 p.m. weight,...

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Bibliographic Details
Published inCanadian journal of psychiatry Vol. 34; no. 8; p. 779
Main Authors Vieweg, W V, Godleski, L S, Hundley, P L, Yank, G R
Format Journal Article
LanguageEnglish
Published United States 01.11.1989
Subjects
Adult
Chronic Disease
Circadian Rhythm
Drinking
Female
Humans
Male
Middle Aged
Pituitary Gland, Posterior - physiopathology
Polyuria - physiopathology
Reference Values
Risk Factors
Schizophrenia - physiopathology
Schizophrenic Psychology
Urodynamics
Water Intoxication - physiopathology
Weight Gain
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Summary:We found diurnal weight gain to be abnormal among 39 chronic schizophrenic patients. The patients were weighed and urine samples obtained weekly for three weeks at 7 a.m. and 4 p.m. We normalized the dirunal weight gain (NDWG) as a percentage by subtracting the 7 a.m. weight from the 4 p.m. weight, multiplying the difference by 100, and then dividing the result by the 7 a.m. weight. NDWG was 2.075 +/- 1.331% for the 38 study patients, .631 +/- .405% for 16 acutely psychotic controls and .511 +/- .351% for 29 normals. Seventy-seven percent of the study patients had abnormal NDWG values and 62% were polyuric. NDWG related to urine volume (n = 39, r = .356, p = .026) with the variability in urine excretion explaining 13% of the variability in NDWG. We discuss factors that may have contributed to our findings.
ISSN:0706-7437
DOI:10.1177/070674378903400807