Syntheses and Reactions of Nitrogen- and Sulfur-Analogs of 2-Piperazinone

Abstract 2-Piperazinone oxime, 2-piperazinoneimine, and 2-piperazinethione were synthesized. The reaction mixture of ethylenediamine and glycolonitrile was treated with an excess amount of hydroxylamine in methanol to give 2-piperazinone oxime in a 53% yield. 2-Piperazinone oxime was easily reduced...

Full description

Saved in:
Bibliographic Details
Published inBulletin of the Chemical Society of Japan Vol. 41; no. 3; pp. 702 - 707
Main Authors Masuzawa, Kuniyoshi, Masaki, Mitsuo, Ohta, Masaki
Format Journal Article
LanguageEnglish
Published Tokyo Chemical Society of Japan 01.01.1968
Online AccessGet full text

Cover

More Information
Summary:Abstract 2-Piperazinone oxime, 2-piperazinoneimine, and 2-piperazinethione were synthesized. The reaction mixture of ethylenediamine and glycolonitrile was treated with an excess amount of hydroxylamine in methanol to give 2-piperazinone oxime in a 53% yield. 2-Piperazinone oxime was easily reduced to 2-piperazinoneimine, which was then treated with hydrogen sulfide to yield 2-piperazinethione. Some reactions of these compounds are described.
ISSN:0009-2673
1348-0634
DOI:10.1246/bcsj.41.702