Periodontitis and Systemic Inflammation : Control of the Local Infection is Associated with a Reduction in Serum Inflammatory Markers

• Published in: Journal of dental research Vol. 83; no. 2; pp. 156 - 160
• Main Authors: D’Aiuto, F., Parkar, M., Andreou, G., Suvan, J., Brett, P.M., Ready, D., Tonetti, M.S.
• Format: Journal Article
• Language: English
• Published: United States SAGE Publications 01.02.2004; SAGE PUBLICATIONS, INC
• Subjects: Aggregatibacter actinomycetemcomitans - isolation & purification; atherosclerosis; Bacteroides - isolation & purification; Biomarkers - blood; C-reactive protein; C-Reactive Protein - analysis; Confidence Intervals; Confounding Factors (Epidemiology); Female; Follow-Up Studies; Humans; infection; inflammation; Inflammation - prevention & control; Inflammation Mediators - blood; Interleukin-6 - blood; Longitudinal Studies; Male; Middle Aged; Periodontal Pocket - microbiology; Periodontal Pocket - therapy; periodontitis; Periodontitis - blood; Periodontitis - microbiology; Periodontitis - prevention & control; Pilot Projects; Porphyromonas gingivalis - isolation & purification; Prospective Studies; Single-Blind Method; atherosclerosis; infection; C-reactive protein; inflammation; periodontitis

Severe periodontitis is associated with elevated inflammatory markers in otherwise healthy populations. However, the nature of this association has not been determined. Our aim was to assess whether the degree of response to periodontal therapy was associated with changes in serological markers of s...