Cochlear implantation for treatment-induced ototoxic deafness in langerhans cell histiocytosis. A case report

A case is presented where the authors carried out a cochlear implantation on a girl whose deafness was induced by cytostatic agents. The normally hearing child was diagnosed with Langerhans cell histiocytosis at the age of 3 years and received polychemotherapy for almost 2 years. By her 5th year, sh...

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Published inEuropean archives of oto-rhino-laryngology Vol. 262; no. 6; pp. 496 - 500
Main Authors TORKOS, Attila, CZIGNER, Jenö, KISS, Jozsef Geza, TOTH, Ferenc, SZAMOSKÖZI, Alice, JORI, Jozsef
Format Journal Article
LanguageEnglish
Published Berlin Springer 01.06.2005
Subjects
Adolescent
Antineoplastic Combined Chemotherapy Protocols - adverse effects
Biological and medical sciences
Cochlear Implantation
Cochlear Implants
Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology
Female
Hearing Loss, Bilateral - chemically induced
Hearing Loss, Bilateral - surgery
Hearing Loss, Sensorineural - chemically induced
Hearing Loss, Sensorineural - surgery
Hematologic and hematopoietic diseases
Histiocytosis, Langerhans-Cell - drug therapy
Humans
Medical sciences
Non tumoral diseases
Other diseases. Hematologic involvement in other diseases
Otorhinolaryngology. Stomatology
Speech Perception
Tomography, X-Ray Computed
Treatment Outcome
Toxicity
Langerhans cell histiocytosis
Cochlear implantation
Auditory disorder
Implantation
Hemopathy
Histiocytosis
Hearing loss
Case study
Chemotherapy
Treatment
Postlingual deafness
Cochlea
ENT disease
Ototoxicity
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Summary:A case is presented where the authors carried out a cochlear implantation on a girl whose deafness was induced by cytostatic agents. The normally hearing child was diagnosed with Langerhans cell histiocytosis at the age of 3 years and received polychemotherapy for almost 2 years. By her 5th year, she started to develop a bilateral, progressive sensorineural hearing loss, necessitating a hearing aid in both ears. While her histiocytosis was cured, her hearing ultimately deteriorated to total deafness on the right and profound hearing loss on the left ear. After 3 years, her hearing aids no longer provided adequate hearing for the postlingually deafened girl. At the age of 14, a cochlear implantation was performed on her right ear with excellent results.
ISSN:0937-4477
1434-4726
DOI:10.1007/s00405-004-0858-1