Effect of milk and fermented milk on iron absorption in ileostomy subjects

• Published in: The American journal of clinical nutrition Vol. 62; no. 6; pp. 1234 - 1238
• Main Authors: Tidehag, P, Sandberg, AS, Hallmans, G, Wing, K, Türk, M, Holm, S, Grahn, E
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Elsevier Inc 01.12.1995; American Society for Clinical Nutrition; American Society for Clinical Nutrition, Inc
• Subjects: Adult; Animals; Biological and medical sciences; Calcium; Calcium, Dietary - analysis; Calcium, Dietary - pharmacokinetics; Calcium, Dietary - pharmacology; Cross-Over Studies; Diet; Diet - standards; Feeding. Feeding behavior; Female; Fermentation; Fundamental and applied biological sciences. Psychology; Humans; Ileostomy; Inositol Phosphates - analysis; Intestinal Absorption - drug effects; Intestinal Absorption - physiology; Iron; Iron - analysis; Iron - pharmacokinetics; Male; Middle Aged; Milk; Milk - chemistry; Milk - metabolism; Milk - standards; Nutrition; Phytic Acid - administration & dosage; Phytic Acid - analysis; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Human; Nutrition; Calcium; Interaction; Gut; Meal; Dairy product; Iron; Skimmilk; Fermented product; Inorganic element; Feeding; Absorption; Cow milk
• ISSN: 0002-9165; 1938-3207
• DOI: 10.1093/ajcn/62.6.1234

This study was undertaken to determine whether milk with its high calcium content adversely affects the absorption of nonheme iron from the diet as greatly as single-meal studies indicate. Nine ileostomy subjects ate a low-fiber, low-phytate diet for 8 consecutive weeks. During the first and eight weeks they drank a 250-mL soft drink with three main meals and an evening snack each day (0.16 g Ca/d). During the two intervening 3-wk periods, they drank the same amount of low-fat milk or fermented low-fat milk (Verum; Hälsofil, Norrmejerier, Umeä, Sweden) according to a formally randomized crossover design (1.4 g Ca/d). During the last 2 d in each of the four periods, apparent iron absorption (balance) from a test diet together with that period’s beverage was measured and the plasma ferritin concentration was determined. There was no decrease in apparent iron absorption during the milk diet periods.