Functional Recovery After Acute Myocardial Infarction

• Published in: Journal of the American College of Cardiology Vol. 52; no. 3; pp. 181 - 189
• Main Authors: Nijveldt, Robin, MD, Beek, Aernout M., MD, Hirsch, Alexander, MD, Stoel, Martin G., MD, Hofman, Mark B.M., PhD, Umans, Victor A.W.M., MD, PhD, Algra, Paul R., MD, PhD, Twisk, Jos W.R., PhD, van Rossum, Albert C., MD, PhD
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 15.07.2008
• Subjects: angiography; Cardiovascular; electrocardiography; Internal Medicine; magnetic resonance imaging; microvascular injury; myocardial infarction; magnetic resonance imaging; myocardial infarction; MVO; LVEF; LV; microvascular injury; angiography; left ventricular ejection fraction; electrocardiography; percutaneous coronary intervention; MBG; Thrombolyis In Myocardial Infarction; myocardial blush grade; left ventricular; AMI; microvascular obstruction; CMR; LGE; cardiovascular magnetic resonance; MCE; systolic wall thickening; SWT; TIMI; PCI; myocardial contrast echocardiography; late gadolinium enhancement; acute myocardial infarction
• ISSN: 0735-1097; 1558-3597
• DOI: 10.1016/j.jacc.2008.04.006

Functional Recovery After Acute Myocardial Infarction: Comparison Between Angiography, Electrocardiography, and Cardiovascular Magnetic Resonance Measures of Microvascular Injury Robin Nijveldt, Aernout M. Beek, Alexander Hirsch, Martin G. Stoel, Mark B. M. Hofman, Victor A. W. M. Umans, Paul R. Algra, Jos W. R. Twisk, Albert C. van Rossum We examined the relation between angiographic, electrocardiographic, and gadolinium-enhanced cardiovascular magnetic resonance (CMR) characteristics of microvascular obstruction, and their predictive value on functional recovery in 60 patients after acute myocardial infarction. Presence of microvascular obstruction as assessed by gadolinium-enhanced CMR was related to electrocardiographic findings, but not to angiographic characteristics of microvascular injury. In a direct comparison in patients after revascularized acute myocardial infarction, microvascular obstruction as detected on late gadolinium-enhanced CMR images proved a more powerful predictor of global and regional functional recovery than all other characteristics, including transmural extent of infarction.