A Quantitative Test of Long‐range Correlations and Compositional Fluctuations in DNA Sequences

Recent findings concerning long‐range correlations and fractals in intron‐containing DNA sequences of living organisms are tested qualitatively and quantitatively. Extending previous studies, we demonstrate that these findings are trivially equivalent to variations of the base‐pair composition in di...

Full description

Saved in:
Bibliographic Details
Published inEuropean journal of biochemistry Vol. 224; no. 2; pp. 365 - 371
Main Authors Chatzidimitriou‐Dreismann, C. Aris, Streffer, R. M. Friedrich, Larhammar, Dan
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Science Ltd 01.09.1994
Subjects
Animals
Base Sequence
Chromosomes, Fungal
DNA - chemistry
Fractals
Humans
Introns
Mice
Saccharomyces cerevisiae - genetics
Sequence Homology, Nucleic Acid
Stochastic Processes
Online AccessGet full text

Cover

More Information
Summary:Recent findings concerning long‐range correlations and fractals in intron‐containing DNA sequences of living organisms are tested qualitatively and quantitatively. Extending previous studies, we demonstrate that these findings are trivially equivalent to variations of the base‐pair composition in different regions of a DNA sequence. It is shown explicitly that a well‐defined scaling or fractal exponent does not exist anywhere. Comparisons of natural DNAs with computer‐generated, artificial sequences are made. The present study reveals that certain natural DNA sequences (especially those with compact genomes) do have stochastic characteristics which are intrinsically different from artificial sequences. The results for 21 DNA sequences of various types from widely different taxa are reported.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
ISSN:0014-2956
1432-1033
DOI:10.1111/j.1432-1033.1994.00365.x