Microvascular changes in the peripheral microcirculation of women with chronic pelvic pain due to congestion
Objective Pelvic venous congestion is a common finding in women with chronic pelvic pain. While the pathophysiology of this condition is poorly understood, there are clear indications that it involves vascular dysfunction. The present studies sought abnormalities in microvascular function in these p...
Saved in:
Published in | BJOG : an international journal of obstetrics and gynaecology Vol. 109; no. 8; pp. 867 - 873 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Science Ltd
01.08.2002
Blackwell |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Objective
Pelvic venous congestion is a common finding in women with chronic pelvic pain. While the pathophysiology of this condition is poorly understood, there are clear indications that it involves vascular dysfunction. The present studies sought abnormalities in microvascular function in these patients.
Design
Prospective longitudinal study.
Setting
A teaching hospital tertiary referral.
Population
Eighteen women with pelvic congestion and 13 nomal women.
Methods
Parameters of microcirculatory function were measured in the calves of women using venous congestion plethysmography during the midfollicular and midluteal phases of the menstrual cycle. The women with pelvic congestion were studied again after treatment for the condition.
Main outcome measures
Isovolumetric venous pressure, microvascular filtration capacity and limb blood flow.
Results
Of the measured parameters of microvascular function, only isovolumetric venous pressure (Pvi) was significantly higher in women with congestion when compared to the controls during the same phase of the cycle. There were no menstrual cycle related differences in any of the other measured parameters in either patients or controls. Following successful treatment for the condition, values of Pvi in women with pelvic congestion were significantly reduced, achieving a level similar to that observed in the controls.
Conclusion
The observed changes in Pvi suggest that this parameter is intimately associated with the pathophysiology of pelvic congestion. The increase in Pvi, without alterations in other measured microvascular parameters, may be attributable to systemic increases in postcapillary resistance secondary to neutrophil activation. These findings support the notion of systemic microvascular dysfunction in these women. |
---|---|
AbstractList | Pelvic venous congestion is a common finding in women with chronic pelvic pain. While the pathophysiology of this condition is poorly understood, there are clear indications that it involves vascular dysfunction. The present studies sought abnormalities in microvascular function in these patients.
Prospective longitudinal study.
A teaching hospital tertiary referral.
Eighteen women with pelvic congestion and 13 normal women.
Parameters of microcirculatory function were measured in the calves of women using venous congestion plethysmography during the midfollicular and midluteal phases of the menstrual cycle. The women with pelvic congestion were studied again after treatment for the condition.
Isovolumetric venous pressure, microvascular filtration capacity and limb blood flow.
Of the measured parameters of microvascular function, only isovolumetric venous pressure (Pvi) was significantly higher in women with congestion when compared to the controls during the same phase of the cycle. There were no menstrual cycle related differences in any of the other measured parameters in either patients or controls. Following successful treatment for the condition, values of Pvi in women with pelvic congestion were significantly reduced, achieving a level similar to that observed in the controls.
The observed changes in Pvi suggest that this parameter is intimately associated with the pathophysiology of pelvic congestion. The increase in Pvi, without alterations in other measured microvascular parameters, may be attributable to systemic increases in postcapillary resistance secondary to neutrophil activation. These findings support the notion of systemic microvascular dysfunction in these women. Objective Pelvic venous congestion is a common finding in women with chronic pelvic pain. While the pathophysiology of this condition is poorly understood, there are clear indications that it involves vascular dysfunction. The present studies sought abnormalities in microvascular function in these patients. Design Prospective longitudinal study. Setting A teaching hospital tertiary referral. Population Eighteen women with pelvic congestion and 13 nomal women. Methods Parameters of microcirculatory function were measured in the calves of women using venous congestion plethysmography during the midfollicular and midluteal phases of the menstrual cycle. The women with pelvic congestion were studied again after treatment for the condition. Main outcome measures Isovolumetric venous pressure, microvascular filtration capacity and limb blood flow. Results Of the measured parameters of microvascular function, only isovolumetric venous pressure (Pvi) was significantly higher in women with congestion when compared to the controls during the same phase of the cycle. There were no menstrual cycle related differences in any of the other measured parameters in either patients or controls. Following successful treatment for the condition, values of Pvi in women with pelvic congestion were significantly reduced, achieving a level similar to that observed in the controls. Conclusion The observed changes in Pvi suggest that this parameter is intimately associated with the pathophysiology of pelvic congestion. The increase in Pvi, without alterations in other measured microvascular parameters, may be attributable to systemic increases in postcapillary resistance secondary to neutrophil activation. These findings support the notion of systemic microvascular dysfunction in these women. OBJECTIVEPelvic venous congestion is a common finding in women with chronic pelvic pain. While the pathophysiology of this condition is poorly understood, there are clear indications that it involves vascular dysfunction. The present studies sought abnormalities in microvascular function in these patients. DESIGNProspective longitudinal study. SETTINGA teaching hospital tertiary referral. POPULATIONEighteen women with pelvic congestion and 13 normal women. METHODSParameters of microcirculatory function were measured in the calves of women using venous congestion plethysmography during the midfollicular and midluteal phases of the menstrual cycle. The women with pelvic congestion were studied again after treatment for the condition. MAIN OUTCOME MEASURESIsovolumetric venous pressure, microvascular filtration capacity and limb blood flow. RESULTSOf the measured parameters of microvascular function, only isovolumetric venous pressure (Pvi) was significantly higher in women with congestion when compared to the controls during the same phase of the cycle. There were no menstrual cycle related differences in any of the other measured parameters in either patients or controls. Following successful treatment for the condition, values of Pvi in women with pelvic congestion were significantly reduced, achieving a level similar to that observed in the controls. CONCLUSIONThe observed changes in Pvi suggest that this parameter is intimately associated with the pathophysiology of pelvic congestion. The increase in Pvi, without alterations in other measured microvascular parameters, may be attributable to systemic increases in postcapillary resistance secondary to neutrophil activation. These findings support the notion of systemic microvascular dysfunction in these women. |
Author | Sutherland, I.A. Foong, L.C. Beard, R.W. Gamble, J. |
Author_xml | – sequence: 1 givenname: L.C. surname: Foong fullname: Foong, L.C. – sequence: 2 givenname: J. surname: Gamble fullname: Gamble, J. – sequence: 3 givenname: I.A. surname: Sutherland fullname: Sutherland, I.A. – sequence: 4 givenname: R.W. surname: Beard fullname: Beard, R.W. |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13822889$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/12197365$$D View this record in MEDLINE/PubMed |
BookMark | eNqNkM1PHCEYh0lj41f9FxouepspXzPAoQc1atvYeGnPhGWYLhsGVthx9b8X3I1ey-V9E57f-8JzAg5CDBYAiFGLy_m2ajHjuEEdES1BiLQIM8La50_g-P3i4K1HDaJEHIGTnFcI4Z4gegiOMMGS0747Bv63Myk-6WxmrxM0Sx3-2QxdgJulhWub3Hppk_ZwqpxxqXIbFwOMI9zGyQa4dZtlCaYYnCkJ_1SLLhOG2cJNhCbWkTXzBXwetc_2bF9Pwd_bmz_XP5r7h7uf15f3jaGyY03HMUNYcIYlYx0bRG8EomwwVKOhF0xqJntGteXM0gXrJEYLye2IqaSEDoSegovd3HWKj3PZrSaXjfVeBxvnrDhBhEvGCyh2YPlbzsmOap3cpNOLwkhV02qlqlBVhapqWr2ZVs8l-nW_Y15MdvgI7tUW4HwPFLnaj0kH4_IHRwUhQsjCfd9xW-fty38_QF39eqgdfQWVKZsG |
CitedBy_id | crossref_primary_10_1016_j_jpsychores_2006_05_003 crossref_primary_10_1016_S0022_5347_06_00514_3 crossref_primary_10_1016_j_sjpain_2011_02_005 |
Cites_doi | 10.1016/S1078-5884(98)80039-7 10.1111/j.1469-7793.1998.611bt.x 10.1111/j.1469-7793.1997.463bh.x 10.1042/cs0980201 10.1016/S0140-6736(84)91165-6 10.1152/jappl.1994.77.4.1801 10.1016/S0140-6736(99)80010-5 10.1016/0140-6736(91)91171-P 10.1159/000061944 10.1111/j.1471-0528.2000.tb11684.x 10.1016/0163-7258(94)00064-A 10.1113/jphysiol.1997.sp021880 10.1113/jphysiol.1993.sp019642 10.1007/s001340050509 10.1159/000179028 10.1042/CS19990362 10.1152/ajplegacy.1948.152.3.471 10.1016/S0002-9378(11)91597-X |
ContentType | Journal Article |
Copyright | 2002 INIST-CNRS |
Copyright_xml | – notice: 2002 INIST-CNRS |
DBID | IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1111/j.1471-0528.2002.01424.x |
DatabaseName | Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE CrossRef MEDLINE - Academic |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1471-0528 |
EndPage | 873 |
ExternalDocumentID | 10_1111_j_1471_0528_2002_01424_x 12197365 13822889 BJO1424 |
Genre | article Journal Article |
GroupedDBID | --- --K .3N .55 .GA .GJ .Y3 05W 0R~ 10A 1B1 1OB 1OC 1~5 23N 24P 33P 36B 3O- 3SF 4.4 4G. 50Y 50Z 51W 51X 52M 52N 52O 52P 52R 52S 52T 52U 52V 52W 52X 53G 5HH 5LA 5RE 5VS 66C 6J9 6P2 6PF 7-5 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A01 A03 AAEDT AAESR AAEVG AAHHS AALRI AANLZ AAONW AAQFI AASGY AAWTL AAXRX AAXUO AAZKR ABCQN ABCUV ABEML ABLJU ABPVW ABQWH ABXGK ACAHQ ACBWZ ACCFJ ACCZN ACFBH ACGFO ACGFS ACGOF ACIUM ACMXC ACPOU ACPRK ACSCC ACXBN ACXQS ADBBV ADBTR ADEOM ADIZJ ADKYN ADMGS ADMUD ADOZA ADXAS ADZMN ADZOD AEEZP AEIGN AEIMD AEQDE AEUQT AEUYR AFBPY AFEBI AFFPM AFGKR AFPWT AFZJQ AHBTC AHEFC AHMBA AIACR AIAGR AITYG AIURR AIWBW AJBDE ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN AMBMR AMYDB ASPBG ATUGU AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BROTX BRXPI BY8 C45 CAG COF CS3 D-6 D-7 D-E D-F DCZOG DPXWK DR2 DRFUL DRMAN DRSTM DUUFO EBS EJD EMOBN EX3 F00 F01 F04 F5P FDB FEDTE FZ0 G-S G.N GODZA H.X HF~ HGLYW HVGLF HZI HZ~ IHE IX1 J0M K48 KBYEO LATKE LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES M41 MEWTI MK4 MRFUL MRMAN MRSTM MSFUL MSMAN MSSTM MXFUL MXMAN MXSTM N04 N05 N9A NEJ NF~ O66 O9- OIG OVD P2P P2W P2X P2Z P4B P4D PALCI PQQKQ Q.N Q11 QB0 R.K RIG RIWAO RJQFR ROL RPZ RWI RX1 SAMSI SEW SSZ SUPJJ TEORI V9Y W8V W99 WBKPD WHWMO WIH WIJ WIK WOHZO WOW WQJ WRC WVDHM WXI WXSBR X7M XG1 XIF XV2 ZXP ZY1 ~IA ~WT AAVGM ABHUG ABMYL ABWRO ACSMX ACXME ADAWD ADDAD AFVGU AGJLS AHPSJ IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c3954-571401874194454d86c8034dc3a0d6849a49643ae74e3b45910b97ef139323d23 |
IEDL.DBID | DR2 |
ISSN | 1470-0328 |
IngestDate | Fri Aug 16 08:48:16 EDT 2024 Fri Aug 23 00:39:21 EDT 2024 Sat Sep 28 07:37:43 EDT 2024 Tue Mar 12 05:32:05 EDT 2024 Sat Aug 24 01:03:44 EDT 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 8 |
Keywords | Human Microcirculation Chronic Menstrual cycle Pathogenesis Pelvis pathology Adult Female Pelvic pain Elderly Plethysmography Venous pressure |
Language | English |
License | CC BY 4.0 |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c3954-571401874194454d86c8034dc3a0d6849a49643ae74e3b45910b97ef139323d23 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 12197365 |
PQID | 72027947 |
PQPubID | 23479 |
PageCount | 7 |
ParticipantIDs | proquest_miscellaneous_72027947 crossref_primary_10_1111_j_1471_0528_2002_01424_x pubmed_primary_12197365 pascalfrancis_primary_13822889 wiley_primary_10_1111_j_1471_0528_2002_01424_x_BJO1424 |
PublicationCentury | 2000 |
PublicationDate | August 2002 |
PublicationDateYYYYMMDD | 2002-08-01 |
PublicationDate_xml | – month: 08 year: 2002 text: August 2002 |
PublicationDecade | 2000 |
PublicationPlace | Oxford, UK |
PublicationPlace_xml | – name: Oxford, UK – name: Oxford – name: England |
PublicationTitle | BJOG : an international journal of obstetrics and gynaecology |
PublicationTitleAlternate | BJOG |
PublicationYear | 2002 |
Publisher | Blackwell Science Ltd Blackwell |
Publisher_xml | – name: Blackwell Science Ltd – name: Blackwell |
References | 1997; 498 1987; ii 1995; 15 1991; 10 1992; 167 2000; 95 1996; 90 1998; 81 1999; 364 1991; 337 1996; 16 1993; 464 1999 1998; 24 1994; 266 1987; 46 1998; 15 1948; 152 1997; 503 2000; 98 1984; ii 2000; 107 1998; 507 1995; 65 1994; 77 Gamble J (e_1_2_6_17_2) 1996; 16 Schmid‐Schonbein GW (e_1_2_6_24_2) 1987; 46 Gamble J (e_1_2_6_16_2) 1996; 16 Stibe E (e_1_2_6_18_2) 1991; 10 Suematsu M (e_1_2_6_19_2) 1994; 266 e_1_2_6_12_2 e_1_2_6_13_2 e_1_2_6_10_2 e_1_2_6_11_2 e_1_2_6_20_2 Bethell DB (e_1_2_6_14_2) 1996; 90 Buttrum SM (e_1_2_6_23_2) 1994; 77 Reginald PW (e_1_2_6_27_2) 1987 e_1_2_6_7_2 Emmanuel AV (e_1_2_6_8_2) 2000; 95 e_1_2_6_9_2 e_1_2_6_4_2 e_1_2_6_3_2 e_1_2_6_6_2 e_1_2_6_5_2 Chappell L (e_1_2_6_26_2) 1999; 364 e_1_2_6_2_2 e_1_2_6_22_2 Festa M (e_1_2_6_15_2) 1998; 81 e_1_2_6_21_2 e_1_2_6_25_2 |
References_xml | – volume: 77 start-page: 1801 year: 1994 end-page: 1810 article-title: Rheological response of neutrophils to different types of stimulation publication-title: J Appl Physiol – volume: 167 start-page: 828 year: 1992 end-page: 833 article-title: Estrogen‐induced uterine vasodilatation is antagonised by l‐nitroarginine methyl ester, an inhibitor of nitric oxide synthesis publication-title: Am J Obstet Gynecol – volume: 65 start-page: 215 year: 1995 end-page: 239 article-title: Control of vascular resistance in the maternal and feto‐placental arterial beds publication-title: Pharmacol Ther – volume: 16 start-page: P333 year: 1996 article-title: Changes in peripheral microvascular parameters in pre‐eclamptic (PET) patients publication-title: Int J Microcirc Clin Exp – volume: 95 start-page: 201 year: 2000 end-page: 207 article-title: Reproducible assessment of vaginal and rectal mucosal and skin blood flow: laser Doppler fluximetry of the pelvic microcirculation publication-title: Clin Sci – volume: 81 start-page: 815P year: 1998 article-title: Microvascular changes in the microcirculation in children with meningococcal septicaemia publication-title: Br J Anaesth – volume: 15 start-page: 265 year: 1995 end-page: 270 article-title: Mechanisms and implications of capillary endothelial swelling and luminal narrowing in low‐flow ischemias publication-title: Int J Microcirc Clin Exp – volume: 337 start-page: 398 year: 1991 end-page: 400 article-title: Pelvic congestion publication-title: Lancet – volume: 10 start-page: 391 year: 1991 article-title: Mercury in Silastic strain gauge (MSG) assessment of microvascular parameters in venous ulceration patients publication-title: Int J Microcirc Clin Exp – volume: 98 start-page: 455 issue: 4 year: 2000 end-page: 460 article-title: Vitamin C modifies the cardiovascular and microvascular responses to cigarette smoke inhalation in man publication-title: Clin Sci – volume: ii start-page: 352 year: 1987 end-page: 353 article-title: Intravenous dihydroergotamine to relieve pelvic congestion with pain in young women publication-title: Lancet – volume: 507 start-page: 611 year: 1998 end-page: 617 article-title: Human calf precapillary resistance decreases in response to small cumulative increases in venous congestion pressure publication-title: J Physiol – volume: 16 start-page: P332 year: 1996 article-title: Peripheral vascular and microvascular changes in cystic fibrosis (CF) publication-title: Int J Microcirc Clin Exp – volume: 364 start-page: 810 year: 1999 end-page: 816 article-title: Effect of antioxidants on the occurrence of pre‐eclampsia in women at increased risk: a randomised trial publication-title: Lancet – volume: 46 start-page: 2397 year: 1987 end-page: 2401 article-title: Capillary plugging by granulocytes and the no‐reflow phenomenon in the microcirculation publication-title: Fed Proc – volume: 90 start-page: P463 year: 1996 article-title: Pathophysiological studies in dengue shock syndrome publication-title: Trans R Soc Trop Med Hyg – volume: 107 start-page: 157 issue: 2 year: 2000 end-page: 164 article-title: Altered peripheral vascular response of women with and without pelvic pain due to congestion publication-title: Br J Obstet Gynaecol – volume: 266 start-page: H2410 year: 1994 end-page: H2415 article-title: Microvascular oxidative stress preceding leukocyte activation elicited by in vivo nitric oxide suppression publication-title: Am J Physiol – volume: 503 start-page: 463 year: 1997 end-page: 467 article-title: Relationship between venous pressure and tissue volume during venous congestion plethysmography in man publication-title: J Physiol – volume: 152 start-page: 471 year: 1948 end-page: 491 article-title: Effective osmotic pressure of the plasma proteins and other quantities associated with the capillary circulation in the hindlimbs of cats and dogs publication-title: Am J Physiol – volume: ii start-page: 946 year: 1984 end-page: 949 article-title: Diagnosis of pelvic varicosities in women with chronic pelvic pain publication-title: Lancet – volume: 498 start-page: 541 year: 1997 end-page: 552 article-title: The effect of passive tilting on microvascular parameters in the human calf: a strain gauge plethysmography study publication-title: J Physiol – volume: 464 start-page: 407 year: 1993 end-page: 422 article-title: A reassessment of mercury in Silastic strain gauge plethysmography for microvascular permeability assessment in man publication-title: J Physiol – volume: 15 start-page: 342 year: 1998 end-page: 349 article-title: Endothelial activation in patients with chronic venous disease publication-title: Eur J Vasc Endovasc Surg – start-page: 12 year: 1999 end-page: 32 – volume: 24 start-page: 18 year: 1998 end-page: 27 article-title: Increased microvascular water permeability in patients with septic shock, assessed with venous congestion plethysmography (VCP) publication-title: Intensive Care Med – volume: 90 start-page: P463 year: 1996 ident: e_1_2_6_14_2 article-title: Pathophysiological studies in dengue shock syndrome publication-title: Trans R Soc Trop Med Hyg contributor: fullname: Bethell DB – volume: 16 start-page: P333 year: 1996 ident: e_1_2_6_17_2 article-title: Changes in peripheral microvascular parameters in pre‐eclamptic (PET) patients publication-title: Int J Microcirc Clin Exp contributor: fullname: Gamble J – ident: e_1_2_6_25_2 doi: 10.1016/S1078-5884(98)80039-7 – ident: e_1_2_6_12_2 doi: 10.1111/j.1469-7793.1998.611bt.x – ident: e_1_2_6_20_2 doi: 10.1111/j.1469-7793.1997.463bh.x – volume: 81 start-page: 815P year: 1998 ident: e_1_2_6_15_2 article-title: Microvascular changes in the microcirculation in children with meningococcal septicaemia publication-title: Br J Anaesth contributor: fullname: Festa M – volume: 95 start-page: 201 year: 2000 ident: e_1_2_6_8_2 article-title: Reproducible assessment of vaginal and rectal mucosal and skin blood flow: laser Doppler fluximetry of the pelvic microcirculation publication-title: Clin Sci doi: 10.1042/cs0980201 contributor: fullname: Emmanuel AV – volume: 10 start-page: 391 year: 1991 ident: e_1_2_6_18_2 article-title: Mercury in Silastic strain gauge (MSG) assessment of microvascular parameters in venous ulceration patients publication-title: Int J Microcirc Clin Exp contributor: fullname: Stibe E – volume: 266 start-page: H2410 year: 1994 ident: e_1_2_6_19_2 article-title: Microvascular oxidative stress preceding leukocyte activation elicited by in vivo nitric oxide suppression publication-title: Am J Physiol contributor: fullname: Suematsu M – start-page: 352 year: 1987 ident: e_1_2_6_27_2 article-title: Intravenous dihydroergotamine to relieve pelvic congestion with pain in young women publication-title: Lancet contributor: fullname: Reginald PW – ident: e_1_2_6_2_2 doi: 10.1016/S0140-6736(84)91165-6 – volume: 77 start-page: 1801 year: 1994 ident: e_1_2_6_23_2 article-title: Rheological response of neutrophils to different types of stimulation publication-title: J Appl Physiol doi: 10.1152/jappl.1994.77.4.1801 contributor: fullname: Buttrum SM – volume: 364 start-page: 810 year: 1999 ident: e_1_2_6_26_2 article-title: Effect of antioxidants on the occurrence of pre‐eclampsia in women at increased risk: a randomised trial publication-title: Lancet doi: 10.1016/S0140-6736(99)80010-5 contributor: fullname: Chappell L – ident: e_1_2_6_3_2 doi: 10.1016/0140-6736(91)91171-P – ident: e_1_2_6_9_2 doi: 10.1159/000061944 – volume: 16 start-page: P332 year: 1996 ident: e_1_2_6_16_2 article-title: Peripheral vascular and microvascular changes in cystic fibrosis (CF) publication-title: Int J Microcirc Clin Exp contributor: fullname: Gamble J – ident: e_1_2_6_7_2 doi: 10.1111/j.1471-0528.2000.tb11684.x – ident: e_1_2_6_6_2 doi: 10.1016/0163-7258(94)00064-A – ident: e_1_2_6_11_2 doi: 10.1113/jphysiol.1997.sp021880 – ident: e_1_2_6_10_2 doi: 10.1113/jphysiol.1993.sp019642 – ident: e_1_2_6_13_2 doi: 10.1007/s001340050509 – ident: e_1_2_6_4_2 doi: 10.1159/000179028 – ident: e_1_2_6_21_2 doi: 10.1042/CS19990362 – ident: e_1_2_6_22_2 doi: 10.1152/ajplegacy.1948.152.3.471 – ident: e_1_2_6_5_2 doi: 10.1016/S0002-9378(11)91597-X – volume: 46 start-page: 2397 year: 1987 ident: e_1_2_6_24_2 article-title: Capillary plugging by granulocytes and the no‐reflow phenomenon in the microcirculation publication-title: Fed Proc contributor: fullname: Schmid‐Schonbein GW |
SSID | ssj0016203 |
Score | 1.7337457 |
Snippet | Objective
Pelvic venous congestion is a common finding in women with chronic pelvic pain. While the pathophysiology of this condition is poorly understood,... Pelvic venous congestion is a common finding in women with chronic pelvic pain. While the pathophysiology of this condition is poorly understood, there are... OBJECTIVEPelvic venous congestion is a common finding in women with chronic pelvic pain. While the pathophysiology of this condition is poorly understood,... |
SourceID | proquest crossref pubmed pascalfrancis wiley |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 867 |
SubjectTerms | Adult Aged Biological and medical sciences Blood Pressure - physiology Chronic Disease Extremities - blood supply Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Longitudinal Studies Medical sciences Microcirculation - physiology Middle Aged Non tumoral diseases Pelvic Pain - physiopathology Peripheral Vascular Diseases - physiopathology Prospective Studies |
Title | Microvascular changes in the peripheral microcirculation of women with chronic pelvic pain due to congestion |
URI | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fj.1471-0528.2002.01424.x https://www.ncbi.nlm.nih.gov/pubmed/12197365 https://search.proquest.com/docview/72027947 |
Volume | 109 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1La9wwEB5KDqUQ-kgfcR-JDr16sa2RJR3b0hACm0BpIDcjWTKEbL0huxtCf31nZG_SDTmE0pN98AhbM2N9I818A_C5c8ah0iFHRRaMzmHuLYbcOl-bgEp2qY57elwfnuLRmTob85-4Fmbgh7jdcGPPSP9rdnDnF_ecXFMorCqTMg0mBRdtTRhPMq8e46Mft0xSZV2lJskkUuRMIbeZ1PPgQBsr1falW9CkdUO3i4fg6Ca6TcvTwQu4WH_YkJVyMVkt_aT9fY_z8f98-Ut4PqJY8WUwu1fwJPY78HQ6ntO_htmU8_zWWa5iqC5eiPNeEN4UTK6c2Axm4hc_155ftWMXMTHvRCKFELxBTIKJupckZtd8cTRCWEWxnAuK4_lojGTewOnB95_fDvOxr0PeSqswV0wSyL0AS4uoMJi6NYXE0EpXhNqgdcgsYS5qjNKjIkTjrY4dgVVZyVDJt7DVz_u4C4LgiixjiW0VO9QUSprWF1XEToXQeVtnUK512FwO9B3N32GPLhueRm7GWTVpGpubDPY2lH0nSGZVGWMz2F9rvyFn5BMW18f5atFo3kqyqDN4NxjFnSytDFrWKoM6qfbRb9N8PTrhu_f_KvgBnqUONilp8SNsLa9W8RMBqaXfSy7yB4HrDa0 |
link.rule.ids | 315,786,790,1382,27957,27958,46329,46753 |
linkProvider | Wiley-Blackwell |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3fa9wwDBajhW0w1v1u1q31w15zJLEcO4_dWLl1vQ5GC30zTuxA6S1Xendl7K-f5OTaXenDGHtKHiKTWFb8SZY-AXxonXGotE9R0QpG5zCtK_Rp5erSeFSyjXXck-NyfIqHZ-psaAfEtTA9P8RNwI0tI_6v2cA5IH3HyjX5wqowMdVglHHV1ogA5SZZv4r-1fcbLqm8LGKbZJLJUiaRW0_ruXektb3qyaWb07S1fb-L-wDpOr6NG9TBFkxXn9bnpVyMlot61Py6w_r4n779GTwdgKzY71fec3gQuhfwcDIc1b-E6YRT_VaJrqIvMJ6L804Q5BTMrxwJDabiBz_XnF81QyMxMWtF5IUQHCMmwcjeSxLTa744GsEvg1jMBLnyfDpGMq_g9ODzyadxOrR2SBtZKUwV8wRyO8C8QlToTdmYTKJvpMt8abByyERhLmgMskZFoKaudGgJr8pC-kK-ho1u1oVtEIRYZB5ybIrQoiZv0jR1VgRslfdtXZUJ5Csl2suewcP-6fno3PI0cj_OwsZptD8T2F3T9q2gJEBlTJXA3kr9luyRD1lcF2bLudUcTapQJ_CmXxW3srQ5aFmqBMqo279-G_vx8Bvfvf1XwT14ND6ZHNmjL8dfd-BxbGgTcxjfwcbiahneE65a1LvRXn4Df44Rzw |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELZQkSokVN4lPFofuGaVxOPXESirUtiCEJV6s5zYkaou2VV3t0L8emacbMtWPSDEKTlkrMQzE39jz3zD2JvWGw9ShxwkWjB4D3ltIeTW18oEkKJNddyTY3V4Aken8nTIf6JamJ4f4mrDjTwj_a_JweehveHkGkNhWZmUaTAqqGhrhHjyLihRkYUffLuikipVlboko0yRE4fcZlbPrSNtLFX3536Bs9b27S5uw6Ob8DatT-MH7Hz9ZX1ayvlotaxHza8bpI__59Mfsp0BxvK3vd09Yndi95htT4aD-idsOqFEv3WaK-_Lixf8rOMIODmxKyc6gyn_Qc81ZxfN0EaMz1qeWCE47RCjYOLuRYnpJV08jhBWkS9nHAN5OhtDmafsZPzh-_vDfGjskDfCSsglsQRSM8DSAkgIRjWmEBAa4YugDFgPRBPmo4YoapAIaWqrY4toVVQiVOIZ2-pmXXzOOOIVUcYSmiq2oDGWNE1dVBFaGUJbW5Wxcq1DN-_5O9yfcY8uHU0jdeOsXJpG9zNjexvKvhYUCKeMsRnbX2vfoTfSEYvv4my1cJr2kizojO32RnEti0uDFkpmTCXV_vXbuHdHX-juxb8K7rPtrwdj9_nj8aeX7F7qZpMSGF-xreXFKr5GULWs95K3_AYqQxB- |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Microvascular+changes+in+the+peripheral+microcirculation+of+women+with+chronic+pelvic+pain+due+to+congestion&rft.jtitle=BJOG+%3A+an+international+journal+of+obstetrics+and+gynaecology&rft.au=FOONG%2C+L.+C&rft.au=GAMBLE%2C+J&rft.au=SUTHERLAND%2C+I.+A&rft.au=BEARD%2C+R.+W&rft.date=2002-08-01&rft.pub=Blackwell&rft.issn=1470-0328&rft.eissn=1471-0528&rft.volume=109&rft.issue=8&rft.spage=867&rft.epage=873&rft_id=info:doi/10.1111%2Fj.1471-0528.2002.01424.x&rft.externalDBID=n%2Fa&rft.externalDocID=13822889 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1470-0328&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1470-0328&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1470-0328&client=summon |