Correlation between central corneal thickness and intraocular pressure in various age groups

• Published in: Srpski arhiv za celokupno lekarstvo Vol. 138; no. 5-6; pp. 279 - 286
• Main Authors: Marjanovic, Ivan, Kontic, Djordje, Hentova-Sencanic, Paraskeva, Markovic, Vujica, Bozic, Marija
• Format: Journal Article
• Language: English
• Published: Serbia Serbian Medical Society 01.05.2010
• Subjects: Adult; age groups; Aging - physiology; central corneal thickness; Corneal Topography; dynamic contour tonometry; Female; Glaucoma - physiopathology; Goldmann applanation tonometry; Humans; Intraocular Pressure; Male; Middle Aged; Tonometry, Ocular
• ISSN: 0370-8179; 2406-0895
• DOI: 10.2298/SARH1006279M

The Pascal Dynamic Contour Tonometer (DCT) is an ophthalmic investigational device which directly calculates the dynamic pulsatile fluctuations in intraocular pressure (IOP) using a piezoelectric pressure sensor embedded in the devices tip. The aim of this study was to compare IOP results obtained with Goldmann applanation tonometer (GAT), and their correlation with central corneal thickness (CCT) in patients of various age groups. We studied 37 patients (17 male and 20 female), divided into three age groups: younger than 40 years; 40-60 years old, and older than 60 years. In the first and second group there were patients rarely and in the third mostly diagnosed and medicamentously compensated glaucoma. In topical anaesthesia, first we measured CCT, with ultrasound pachimeter, then IOP with DCT and GAT. Statistically significant difference between measurements of IOP with the DCT and GAT appeared in all groups: I mean diff. -1.71 +/- 1.27 mm; p < 0.0001; II mean diff. -1.19 +/- 1.06 mm; p < 0.0001; III mean diff. -1.69 +/- 1.67 mm; p < 0.0001. CCT was in indirect correlation with the values of IOP measured both with the DCT and GAT in the first and third, while it was in the direct correlation with these values in the second group. CCT had no influence on IOP measurements both with the DCT and GAT in none of the groups. The DCT cannot replace GAT, but it is a reliable device for the measurement of IOP particularly in corneal deformations (keratoconus, after corneal refractive surgery, corneal scars, etc.).