Multifunctional upconverting nanoparticles for near-infrared triggered and synergistic antibacterial resistance therapy

To integrate photodynamic therapy with photothermal therapy for improved multidrug-resistant bacteria therapy, we have constructed a novel multifunctional core/satellite nanostructure by decorating CuS nanoparticles onto the surface of NaYF4:Mn/Yb/Er@photosensitizer doped SiO2. This system exhibited...

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Published inChemical communications (Cambridge, England) Vol. 50; no. 72; pp. 10488 - 10490
Main Authors Yin, Meili, Li, Zhenhua, Ju, Enguo, Wang, Zhenzhen, Dong, Kai, Ren, Jinsong, Qu, Xiaogang
Format Journal Article
LanguageEnglish
Published England 18.09.2014
Subjects
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Antiinfectives and antibacterials
Bacteria
Communication satellites
Copper - chemistry
Drug Resistance, Multiple, Bacterial - drug effects
Drug Resistance, Multiple, Bacterial - radiation effects
Escherichia coli
Escherichia coli - drug effects
Escherichia coli - radiation effects
Fluorides - chemistry
Infrared Rays
Methicillin-Resistant Staphylococcus aureus - drug effects
Methicillin-Resistant Staphylococcus aureus - radiation effects
Methylene Blue - chemistry
Nanoparticles
Nanoparticles - chemistry
Photodynamic therapy
Photosensitizing Agents - chemistry
Silicon Dioxide - chemistry
Staphylococcus
Surface chemistry
Therapy
Yttrium - chemistry
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Summary:To integrate photodynamic therapy with photothermal therapy for improved multidrug-resistant bacteria therapy, we have constructed a novel multifunctional core/satellite nanostructure by decorating CuS nanoparticles onto the surface of NaYF4:Mn/Yb/Er@photosensitizer doped SiO2. This system exhibited a superior antibacterial activity towards drug-resistant Staphylococcus aureus and Escherichia coli.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc04584j