Prenylated isoflavones from Cudrania tricuspidata inhibit NO production in RAW 264.7 macrophages and suppress HL-60 cells proliferation

Inhibitory effects of NO production in RAW 264.7 macrophages guided the isolation of nine prenylated isoflavones, including a new cudraisoflavone L (1) and eight known metabolites furowanin B (2), erysubin A (3), wighteone (4), lupalbigenin (5), laburnetin (6), isolupalbigenin (7), 6,8-diprenylorobo...

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Published inJournal of asian natural products research Vol. 19; no. 5; pp. 510 - 518
Main Authors Tuan Anh, Hoang Le, Tuan, Do Thanh, Trang, Do Thi, Tai, Bui Huu, Nhiem, Nguyen Xuan, Yen, Pham Hai, Kiem, Phan Van, Minh, Chau Van, Duc, Tran Minh, Kang, Hee Kyoung, Kim, Youn Chul, Kim, Young Ho
Format Journal Article
LanguageEnglish
Published ABINGDON Taylor & Francis 01.05.2017
Taylor & Francis Ltd
Subjects
Animals
Anti-Inflammatory Agents, Non-Steroidal - chemistry
Anti-Inflammatory Agents, Non-Steroidal - isolation & purification
Anti-Inflammatory Agents, Non-Steroidal - pharmacology
anti-leukemia
Chemistry
Chemistry, Applied
Chemistry, Medicinal
cudraisoflavone L
Cudrania tricuspidata
Cytoprotection - drug effects
HL-60 Cells
Humans
Isoflavones - chemistry
Isoflavones - isolation & purification
Isoflavones - pharmacology
Life Sciences & Biomedicine
Macrophages - drug effects
Mice
Molecular Structure
Moraceae - chemistry
Nitric Oxide - biosynthesis
NO inhibitor
Pharmacology & Pharmacy
Physical Sciences
Plant Roots - chemistry
Plant Sciences
Prenylated isoflavone
Prenylation
Science & Technology
FRUITS
NO inhibitor
cudraisoflavone L
BARK
ROOTS
FLAVONOIDS
ERYTHRINA
Prenylated isoflavone
Cudrania tricuspidata
anti-leukemia
XANTHONES
EXTRACT
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Abstract Inhibitory effects of NO production in RAW 264.7 macrophages guided the isolation of nine prenylated isoflavones, including a new cudraisoflavone L (1) and eight known metabolites furowanin B (2), erysubin A (3), wighteone (4), lupalbigenin (5), laburnetin (6), isolupalbigenin (7), 6,8-diprenylorobol (8), millewanin H (9) from the leaves of Cudrania tricuspidata. At the concentration of 10 μM, compounds 1, 2, and 4 significantly inhibited NO production with the inhibitory values of 72.5 ± 2.4, 66.9 ± 1.8, and 55.4 ± 2.7%, respectively. In addition, all of isolated compounds 1-9 showed promising cytotoxic effects toward HL-60 cells (IC 50 4.3 ± 0.7 to 18.0 ± 1.7 μM).
AbstractList Inhibitory effects of NO production in RAW 264.7 macrophages guided the isolation of nine prenylated isoflavones, including a new cudraisoflavone L (1) and eight known metabolites furowanin B (2), erysubin A (3), wighteone (4), lupalbigenin (5), laburnetin (6), isolupalbigenin (7), 6,8-diprenylorobol (8), millewanin H (9) from the leaves of Cudrania tricuspidata. At the concentration of 10 μM, compounds 1, 2, and 4 significantly inhibited NO production with the inhibitory values of 72.5 ± 2.4, 66.9 ± 1.8, and 55.4 ± 2.7%, respectively. In addition, all of isolated compounds 1-9 showed promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 μM).
Inhibitory effects of NO production in RAW 264.7 macrophages guided the isolation of nine prenylated isoflavones, including a new cudraisoflavone L (1) and eight known metabolites furowanin B (2), erysubin A (3), wighteone (4), lupalbigenin (5), laburnetin (6), isolupalbigenin (7), 6,8-diprenylorobol (8), millewanin H (9) from the leaves of Cudrania tricuspidata. At the concentration of 10 μM, compounds 1, 2, and 4 significantly inhibited NO production with the inhibitory values of 72.5 ± 2.4, 66.9 ± 1.8, and 55.4 ± 2.7%, respectively. In addition, all of isolated compounds 1-9 showed promising cytotoxic effects toward HL-60 cells (IC50 4.3 ± 0.7 to 18.0 ± 1.7 μM).
Inhibitory effects of NO production in RAW 264.7 macrophages guided the isolation of nine prenylated isoflavones, including a new cudraisoflavone L (1) and eight known metabolites furowanin B (2), erysubin A (3), wighteone (4), lupalbigenin (5), laburnetin (6), isolupalbigenin (7), 6,8-diprenylorobol (8), millewanin H (9) from the leaves of Cudrania tricuspidata. At the concentration of 10M, compounds 1, 2, and 4 significantly inhibited NO production with the inhibitory values of 72.5 +/- 2.4, 66.9 +/- 1.8, and 55.4 +/- 2.7%, respectively. In addition, all of isolated compounds 1-9 showed promising cytotoxic effects toward HL-60 cells (IC50 4.3 +/- 0.7 to 18.0 +/- 1.7M).
Inhibitory effects of NO production in RAW 264.7 macrophages guided the isolation of nine prenylated isoflavones, including a new cudraisoflavone L (1) and eight known metabolites furowanin B (2), erysubin A (3), wighteone (4), lupalbigenin (5), laburnetin (6), isolupalbigenin (7), 6,8-diprenylorobol (8), millewanin H (9) from the leaves of Cudrania tricuspidata. At the concentration of 10 μM, compounds 1, 2, and 4 significantly inhibited NO production with the inhibitory values of 72.5 ± 2.4, 66.9 ± 1.8, and 55.4 ± 2.7%, respectively. In addition, all of isolated compounds 1-9 showed promising cytotoxic effects toward HL-60 cells (IC 4.3 ± 0.7 to 18.0 ± 1.7 μM).
Inhibitory effects of NO production in RAW 264.7 macrophages guided the isolation of nine prenylated isoflavones, including a new cudraisoflavone L (1) and eight known metabolites furowanin B (2), erysubin A (3), wighteone (4), lupalbigenin (5), laburnetin (6), isolupalbigenin (7), 6,8-diprenylorobol (8), millewanin H (9) from the leaves of Cudrania tricuspidata. At the concentration of 10 μM, compounds 1, 2, and 4 significantly inhibited NO production with the inhibitory values of 72.5 ± 2.4, 66.9 ± 1.8, and 55.4 ± 2.7%, respectively. In addition, all of isolated compounds 1-9 showed promising cytotoxic effects toward HL-60 cells (IC 50 4.3 ± 0.7 to 18.0 ± 1.7 μM).
Author Nhiem, Nguyen Xuan
Tuan Anh, Hoang Le
Kiem, Phan Van
Kang, Hee Kyoung
Trang, Do Thi
Yen, Pham Hai
Duc, Tran Minh
Kim, Youn Chul
Tuan, Do Thanh
Tai, Bui Huu
Minh, Chau Van
Kim, Young Ho
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Cites_doi 10.1016/j.bmcl.2005.08.099
10.1002/ptr.3577
10.1021/acs.jafc.5b00903
10.1021/np500364x
10.1016/j.bmcl.2009.07.098
10.3184/174751913X13647406965542
10.1021/np800418j
10.1016/j.fitote.2012.12.006
10.1016/j.bmc.2004.01.030
10.3390/molecules200611173
10.1021/np030481a
10.1016/j.foodchem.2013.11.091
10.1016/j.bmc.2009.02.042
10.1016/j.phytochem.2014.10.021
10.1016/j.bmcl.2007.10.007
10.1515/znc-2000-7-804
10.1016/S0031-9422(00)81531-9
10.1016/0031-9422(96)00128-8
10.1248/cpb.54.1530
10.3987/COM-98-8334
10.1142/S0192415X01000332
10.1016/0031-9422(95)00609-5
10.1016/S0031-9422(00)98025-7
10.1016/0031-9422(95)00029-7
10.1002/ptr.v26.4
10.1021/np050341w
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Issue 5
Keywords FRUITS
NO inhibitor
cudraisoflavone L
BARK
ROOTS
FLAVONOIDS
ERYTHRINA
Prenylated isoflavone
Cudrania tricuspidata
anti-leukemia
XANTHONES
EXTRACT
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References Lee, BW (WOS:000233206300040) 2005; 15
Seo, EJ (WOS:000253489000003) 2007; 17
LANE, GA (WOS:A1987F436700060) 1987; 26
Han, XH (WOS:000262761700031) 2009; 72
Ryu, YB (WOS:000268863800002) 2009; 19
Seo, WG (WOS:000170494500012) 2001; 29
Shan, WG (WOS:000321023400008) 2013
Ryu, YB (WOS:000264637300013) 2009; 17
SATO, H (WOS:A1995RH33200033) 1995; 39
Pistelli, L (WOS:A1996UW00600035) 1996; 42
Hiep, NT (WOS:000350527400017) 2015; 111
Lee, H (WOS:000302620000019) 2012; 26
Zou, YS (WOS:000220754600012) 2004; 12
Quang, TH (WOS:000357992700103) 2015; 20
Morikawa, T (WOS:000242481000007) 2006; 54
NKENGFACK, AE (WOS:A1989AT31500065) 1989; 28
Shi, L (WOS:000332132300041) 2014; 152
Ito, C (WOS:000235106500030) 2006; 69
Kwon, J (WOS:000340861800018) 2014; 77
Tanaka, H (WOS:000077840900024) 1998; 48
Lee, BW (WOS:000227927700034) 2005; 68
Lee, IK (WOS:A1996TL56900036) 1996; 41
Lee, T (WOS:000356316800018) 2015; 63
Maximo, P (WOS:000088827100004) 2000; 55
Zheng, ZP (WOS:000316531400034) 2013; 84
CIT0010
CIT0012
CIT0011
CIT0014
CIT0013
CIT0016
CIT0015
CIT0017
CIT0019
CIT0021
CIT0020
CIT0001
CIT0023
CIT0022
Maximo P. (CIT0018) 2000; 55
CIT0003
CIT0025
CIT0002
CIT0024
CIT0005
CIT0004
CIT0007
CIT0006
CIT0009
CIT0008
References_xml – volume: 54
  start-page: 1530
  year: 2006
  ident: WOS:000242481000007
  article-title: Structures of new flavonoids, erycibenins D, E, and F, and NO production inhibitors from Erycibe expansa originating in Thailand
  publication-title: CHEMICAL & PHARMACEUTICAL BULLETIN
  contributor:
    fullname: Morikawa, T
– volume: 15
  start-page: 5548
  year: 2005
  ident: WOS:000233206300040
  article-title: Antioxidant and cytotoxic activities of xanthones from Cudrania tricuspidata
  publication-title: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
  doi: 10.1016/j.bmcl.2005.08.099
  contributor:
    fullname: Lee, BW
– volume: 26
  start-page: 594
  year: 2012
  ident: WOS:000302620000019
  article-title: The Fruits of Cudrania tricuspidata Suppress Development of Atopic Dermatitis in NC/Nga Mice
  publication-title: PHYTOTHERAPY RESEARCH
  doi: 10.1002/ptr.3577
  contributor:
    fullname: Lee, H
– volume: 63
  start-page: 5459
  year: 2015
  ident: WOS:000356316800018
  article-title: Effects of Cudrania tricuspidata Fruit Extract and Its Active Compound, 5,7,3 ',4 '-Tetrahydroxy-6,8-diprenylisoflavone, on the High-Affinity IgE Receptor-Mediated Activation of Syk in Mast Cells
  publication-title: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
  doi: 10.1021/acs.jafc.5b00903
  contributor:
    fullname: Lee, T
– volume: 77
  start-page: 1893
  year: 2014
  ident: WOS:000340861800018
  article-title: Neuroprotective Xanthones from the Root Bark of Cudrania tricuspidata
  publication-title: JOURNAL OF NATURAL PRODUCTS
  doi: 10.1021/np500364x
  contributor:
    fullname: Kwon, J
– volume: 42
  start-page: 1455
  year: 1996
  ident: WOS:A1996UW00600035
  article-title: Isoflavonoids and chalcones from Anthyllis hermanniae
  publication-title: PHYTOCHEMISTRY
  contributor:
    fullname: Pistelli, L
– volume: 41
  start-page: 213
  year: 1996
  ident: WOS:A1996TL56900036
  article-title: Cytotoxic benzyl dihydroflavonols from Cudrania tricuspidata
  publication-title: PHYTOCHEMISTRY
  contributor:
    fullname: Lee, IK
– volume: 48
  start-page: 2661
  year: 1998
  ident: WOS:000077840900024
  article-title: Two new isoflavones from Erythrina suberosa var. glabrescences
  publication-title: HETEROCYCLES
  contributor:
    fullname: Tanaka, H
– volume: 19
  start-page: 4912
  year: 2009
  ident: WOS:000268863800002
  article-title: Structural characteristics of flavanones and flavones from Cudrania tricuspidata for neuraminidase inhibition
  publication-title: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
  doi: 10.1016/j.bmcl.2009.07.098
  contributor:
    fullname: Ryu, YB
– start-page: 285
  year: 2013
  ident: WOS:000321023400008
  article-title: A new prenylated stilbene derivative from the roots of Cudrania tricuspidata
  publication-title: JOURNAL OF CHEMICAL RESEARCH
  doi: 10.3184/174751913X13647406965542
  contributor:
    fullname: Shan, WG
– volume: 69
  start-page: 138
  year: 2006
  ident: WOS:000235106500030
  article-title: Isoflavonoids with antiestrogenic activity from Millettia pachycarpa
  publication-title: JOURNAL OF NATURAL PRODUCTS
  contributor:
    fullname: Ito, C
– volume: 72
  start-page: 164
  year: 2009
  ident: WOS:000262761700031
  article-title: Prenylated and Benzylated Flavonoids from the Fruits of Cudrania tricuspidata
  publication-title: JOURNAL OF NATURAL PRODUCTS
  doi: 10.1021/np800418j
  contributor:
    fullname: Han, XH
– volume: 84
  start-page: 242
  year: 2013
  ident: WOS:000316531400034
  article-title: Characterization of tyrosinase inhibitors in the twigs of Cudrania tricuspidata and their structure-activity relationship study
  publication-title: FITOTERAPIA
  doi: 10.1016/j.fitote.2012.12.006
  contributor:
    fullname: Zheng, ZP
– volume: 12
  start-page: 1947
  year: 2004
  ident: WOS:000220754600012
  article-title: Cytotoxic isoprenylated xanthones from Cudrania tricuspidata
  publication-title: BIOORGANIC & MEDICINAL CHEMISTRY
  doi: 10.1016/j.bmc.2004.01.030
  contributor:
    fullname: Zou, YS
– volume: 20
  start-page: 11173
  year: 2015
  ident: WOS:000357992700103
  article-title: Protein Tyrosine Phosphatase 1B Inhibitors from the Roots of Cudrania tricuspidata
  publication-title: MOLECULES
  doi: 10.3390/molecules200611173
  contributor:
    fullname: Quang, TH
– volume: 39
  start-page: 673
  year: 1995
  ident: WOS:A1995RH33200033
  article-title: ISOFLAVONES FROM PODS OF LABURNUM ANAGYROIDES
  publication-title: PHYTOCHEMISTRY
  contributor:
    fullname: SATO, H
– volume: 29
  start-page: 313
  year: 2001
  ident: WOS:000170494500012
  article-title: Ethyl acetate extract of the stem bark of Cudrania tricuspidata induces apoptosis in human leukemia HL-60 cells
  publication-title: AMERICAN JOURNAL OF CHINESE MEDICINE
  contributor:
    fullname: Seo, WG
– volume: 68
  start-page: 456
  year: 2005
  ident: WOS:000227927700034
  article-title: Cytotoxic xanthones from Cudrania tricuspidata
  publication-title: JOURNAL OF NATURAL PRODUCTS
  doi: 10.1021/np030481a
  contributor:
    fullname: Lee, BW
– volume: 26
  start-page: 295
  year: 1987
  ident: WOS:A1987F436700060
  article-title: ISOFLAVONES FROM LUPINUS-ANGUSTIFOLIUS ROOT
  publication-title: PHYTOCHEMISTRY
  contributor:
    fullname: LANE, GA
– volume: 55
  start-page: 506
  year: 2000
  ident: WOS:000088827100004
  article-title: Flavonoids from Ulex species
  publication-title: ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
  contributor:
    fullname: Maximo, P
– volume: 152
  start-page: 291
  year: 2014
  ident: WOS:000332132300041
  article-title: Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata
  publication-title: FOOD CHEMISTRY
  doi: 10.1016/j.foodchem.2013.11.091
  contributor:
    fullname: Shi, L
– volume: 17
  start-page: 2744
  year: 2009
  ident: WOS:000264637300013
  article-title: Characteristic of neuraminidase inhibitory xanthones from Cudrania tricuspidata
  publication-title: BIOORGANIC & MEDICINAL CHEMISTRY
  doi: 10.1016/j.bmc.2009.02.042
  contributor:
    fullname: Ryu, YB
– volume: 111
  start-page: 141
  year: 2015
  ident: WOS:000350527400017
  article-title: Isoflavones with neuroprotective activities from fruits of Cudrania tricuspidata
  publication-title: PHYTOCHEMISTRY
  doi: 10.1016/j.phytochem.2014.10.021
  contributor:
    fullname: Hiep, NT
– volume: 17
  start-page: 6421
  year: 2007
  ident: WOS:000253489000003
  article-title: Xanthones from Cudrania tricuspidata displaying potent alpha-glucosidase inhibition
  publication-title: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
  doi: 10.1016/j.bmcl.2007.10.007
  contributor:
    fullname: Seo, EJ
– volume: 28
  start-page: 2522
  year: 1989
  ident: WOS:A1989AT31500065
  article-title: ERYTHRINA STUDIES .12. 8-PRENYLLUTEONE, A PRENYLATED ISOFLAVONE FROM ERYTHRINA-ERIOTRIOCHA
  publication-title: PHYTOCHEMISTRY
  contributor:
    fullname: NKENGFACK, AE
– ident: CIT0022
  doi: 10.1021/np030481a
– ident: CIT0007
  doi: 10.1021/np500364x
– volume: 55
  start-page: 506
  year: 2000
  ident: CIT0018
  publication-title: Z. Naturforsch., C: J. Biosci
  doi: 10.1515/znc-2000-7-804
  contributor:
    fullname: Maximo P.
– ident: CIT0015
  doi: 10.1016/S0031-9422(00)81531-9
– ident: CIT0021
  doi: 10.3184/174751913X13647406965542
– ident: CIT0016
  doi: 10.1016/0031-9422(96)00128-8
– ident: CIT0020
  doi: 10.1248/cpb.54.1530
– ident: CIT0004
  doi: 10.1021/acs.jafc.5b00903
– ident: CIT0014
  doi: 10.3987/COM-98-8334
– ident: CIT0025
  doi: 10.1142/S0192415X01000332
– ident: CIT0003
  doi: 10.1021/np800418j
– ident: CIT0005
  doi: 10.1016/j.bmc.2009.02.042
– ident: CIT0023
  doi: 10.1016/j.bmc.2004.01.030
– ident: CIT0024
  doi: 10.1016/0031-9422(95)00609-5
– ident: CIT0011
  doi: 10.1016/j.bmcl.2007.10.007
– ident: CIT0019
  doi: 10.1016/S0031-9422(00)98025-7
– ident: CIT0010
  doi: 10.1016/j.bmcl.2009.07.098
– ident: CIT0017
  doi: 10.1016/0031-9422(95)00029-7
– ident: CIT0002
  doi: 10.1002/ptr.v26.4
– ident: CIT0012
  doi: 10.1016/j.fitote.2012.12.006
– ident: CIT0006
  doi: 10.1016/j.bmcl.2005.08.099
– ident: CIT0008
  doi: 10.1016/j.phytochem.2014.10.021
– ident: CIT0009
  doi: 10.3390/molecules200611173
– ident: CIT0013
  doi: 10.1021/np050341w
– ident: CIT0001
  doi: 10.1016/j.foodchem.2013.11.091
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Snippet Inhibitory effects of NO production in RAW 264.7 macrophages guided the isolation of nine prenylated isoflavones, including a new cudraisoflavone L (1) and...
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SubjectTerms Animals
Anti-Inflammatory Agents, Non-Steroidal - chemistry
Anti-Inflammatory Agents, Non-Steroidal - isolation & purification
Anti-Inflammatory Agents, Non-Steroidal - pharmacology
anti-leukemia
Chemistry
Chemistry, Applied
Chemistry, Medicinal
cudraisoflavone L
Cudrania tricuspidata
Cytoprotection - drug effects
HL-60 Cells
Humans
Isoflavones - chemistry
Isoflavones - isolation & purification
Isoflavones - pharmacology
Life Sciences & Biomedicine
Macrophages - drug effects
Mice
Molecular Structure
Moraceae - chemistry
Nitric Oxide - biosynthesis
NO inhibitor
Pharmacology & Pharmacy
Physical Sciences
Plant Roots - chemistry
Plant Sciences
Prenylated isoflavone
Prenylation
Science & Technology
Title Prenylated isoflavones from Cudrania tricuspidata inhibit NO production in RAW 264.7 macrophages and suppress HL-60 cells proliferation
URI https://www.tandfonline.com/doi/abs/10.1080/10286020.2016.1232253
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Volume 19
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