Supplementation of Ocean-Based Advance Protein Powder (APP) for Restoration of Body Growth, Bone Development and Immune Functions in Protein Malnourished Mice: Implications for Preventing Child Malnutrition

• Published in: Ecology of food and nutrition Vol. 59; no. 5; pp. 552 - 574
• Main Authors: Yang, Kristen P., Wong, Carmen P., Khanna, Sunil K., Bray, Tammy M.
• Format: Journal Article
• Language: English
• Published: United States Routledge 02.09.2020; Taylor & Francis Ltd
• Subjects: Advance Protein Powder; Body weight; Bone growth; Bone mass; Bone mineral content; Bycatch; Casein; child malnutrition; immune functions; Immune response; Malnutrition; Muscles; Protein malnutrition model; Protein sources; Proteins; Public health; Spleen; Supplements; sustainable protein source; sustainable protein source; child malnutrition; immune functions; Advance Protein Powder; Protein malnutrition model
• ISSN: 0367-0244; 1543-5237
• DOI: 10.1080/03670244.2020.1754811

Child malnutrition is a global public health challenge. A protein malnutrition (PM) model in young mice was established in this study. The efficacy of an ocean-based protein (APP) extracted from by-catch fish as compared to casein and soy on restoring body weight, bone growth, and immunity of PM mice was evaluated. Results show that supplementation of APP increases body weight, lean muscle mass, bone area, mineral content and density. APP supplementation increases spleen, thymus weight, and interlukin-6 production. In conclusion, APP is an alternative source of protein to effectively restore body weight, bone growth and immune function of PM mice.