Ameloblastic carcinoma: Report of an aggressive case with multiple bony metastases

• Published in: American journal of otolaryngology Vol. 24; no. 1; pp. 64 - 69
• Main Authors: Datta, Rajiv, Winston, Janet S., Diaz-Reyes, Gustavo, Loree, Thom R., Myers, Larry, Kuriakose, M.Abraham, Rigual, Nestor R., Hicks, Wesley L.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.01.2003; Elsevier; Elsevier Limited
• Subjects: Adult; Ameloblastoma - pathology; Ameloblastoma - secondary; Ameloblastoma - surgery; Biological and medical sciences; Bone Neoplasms - secondary; Carcinoma - pathology; Carcinoma - secondary; Carcinoma - surgery; Facial bones, jaws, teeth, parodontium: diseases, semeiology; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics; Humans; Male; Mandibular Neoplasms - pathology; Mandibular Neoplasms - surgery; Maxillofacial surgery. Dental surgery. Orthodontics; Medical sciences; Mouth Neoplasms - pathology; Mouth Neoplasms - surgery; Neck Dissection; Neoplasm Invasiveness; Neoplasms, Multiple Primary - pathology; Neoplasms, Multiple Primary - surgery; Otorhinolaryngology. Stomatology; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tumors; Radionuclide study; Carcinoma; Diseases of the osteoarticular system; Male; Scintigraphy; Histopathology; Surgery; Adamantoblast; ENT disease; Adult; Diagnosis; Ameloblastic carcinoma; Maxillary disease; Human; Stomatology; Treatment efficiency; Maxillofacial; Exploration; Malignant tumor; Case study; Pathology; Symptomatology; Adamantinoma; Odontogenic tumor; Treatment; Age 20-29; Medical imagery
• ISSN: 0196-0709; 1532-818X
• DOI: 10.1053/ajot.2003.15

Ameloblastic carcinoma is a rare primary tumor of the maxillofacial skeleton with a distinct predilection for the mandible. These lesions may initially show histologic features of ameloblastoma that dedifferentiate over time. Other ameloblastic carcinomas initially present with morphologic features suggestive of ameloblastoma with areas of epithelial dedifferentiation. We herein report a rare case of aggressive ameloblastic carcinoma in a 22-year-old white man who developed widespread bony metastases and expired 4 years after initial diagnosis. (Am J Otolaryngol 2003;24:64-69. Copyright 2003, Elsevier Science (USA). All rights reserved.)